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471526

Sigma-Aldrich

1-Dimethylamino-2-propanol

≥99%

Sinonimo/i:

N,N-Dimethylisopropanolamine

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About This Item

Formula condensata:
CH3CH(OH)CH2N(CH3)2
Numero CAS:
108-16-7
Peso molecolare:
103.16
Beilstein:
1209244
Numero CE:
203-556-4
Numero MDL:
MFCD00004532
Codice UNSPSC:
12352100
ID PubChem:
24870740
NACRES:
NA.22

Densità del vapore

3.6 (vs air)

Livello qualitativo

200

Tensione di vapore

8 mmHg ( 20 °C)

Saggio

≥99%

Indice di rifrazione

n20/D 1.419 (lit.)

P. ebollizione

121-127 °C (lit.)

Densità

0.837 g/mL at 25 °C (lit.)

Stringa SMILE

CC(O)CN(C)C

InChI

1S/C5H13NO/c1-5(7)4-6(2)3/h5,7H,4H2,1-3H3
NCXUNZWLEYGQAH-UHFFFAOYSA-N

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Descrizione generale

1-Dimethylamino-2-propanol (1DMA2P, DMAPH), a tertiary amine, is a dimethylamino-alcohol having high boiling point. It is a potent protector against mechlorethamine cytotoxicity and inhibitor of choline uptake. Kinetics of homogeneous reaction of carbon dioxide (CO2) with 1-dimethylamino-2-propanol in water has been investigated using stopped-flow technique.

Applicazioni

1-Dimethylamino-2-propanol solution may be used in the synthesis of the following:
  • novel unsymmetrical 2,3,9,10,16,17,23-heptakis(alkoxyl)-24-mono(dimethylaminoalkoxyl)phthalocyanine compounds
  • homoleptic nickel(II) aminoalkoxide
  • Adduct with cobalt(II) 2,4-pentanedionate (acac)

Avvertenze

Danger

Indicazioni di pericolo

H226,H302,H314

Classi di pericolo

Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B

Codice della classe di stoccaggio

3 - Flammable liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

78.8 °F - DIN 51755 Part 1

Punto d’infiammabilità (°C)

26 °C - DIN 51755 Part 1

Dispositivi di protezione individuale

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

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Certificati d'analisi (COA)

Lot/Batch Number
MKCL5037
MKCK9089
SHBL3140
SHBL1243
SHBL0068

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Sigma-Aldrich

149993

3-Diethylamino-1-propanol

2-[2-(Dimethylamino)ethoxy]ethanol 98%

Sigma-Aldrich

424552

2-[2-(Dimethylamino)ethoxy]ethanol

2-Dimethylaminoethanol ≥99.5%

Sigma-Aldrich

471453

2-Dimethylaminoethanol

Zhaopin Bai et al.
Inorganic chemistry, 49(19), 9005-9011 (2010-09-04)
A new pathway by means of transetherification has been developed to synthesize novel unsymmetrical 2,3,9,10,16,17,23-heptakis(alkoxyl)-24-mono(dimethylaminoalkoxyl)phthalocyanine compounds. Cyclic tetramerization of 4,5-di(alkoxyl)phthalonitrile in refluxing dimethylamino-alcohol with high boiling point such as dimethylaminoethanol (DMAE) and 1-dimethylamino-2-propanol in the presence of lithium and pyrazino[2,3-f][1,10]phenanthroline-2,3-dicarbonitrile
S A Naujokaitis et al.
Journal of pharmaceutical sciences, 73(1), 34-39 (1984-01-01)
The structure-activity relationships of 2-dimethylaminoethanol and its analogues as protectors against mechlorethamine cytotoxicity and as inhibitors of choline uptake were evaluated. Of a series of inhibitors and protectors, 2-dimethylaminoethanol was the most potent inhibitor of choline uptake and the most
Synthesis and molecular structures of cobalt (II) ?-diketonate complexes as new MOCVD precursors for cobalt oxide films.
Pasko S, et al.
Polyhedron, 23(5), 735-741 (2004)
Jaimie L Gosselin et al.
The journal of physical chemistry. A, 110(12), 4251-4255 (2006-03-24)
The energy flow and fragmentation dynamics of N,N-dimethylisopropylamine (DMIPA) upon excitation to the 3p Rydberg states has been investigated with use of time-resolved photoelectron and mass spectrometry. The 3p states are short-lived, with a lifetime of 701 +/- 45 fs.
Soluble Ni II alkoxides based on dimethylaminoisopropoxide ligands: molecular structure of [Li (Pr i OH) Ni (η 2-OR)2 Cl]2 and of cis-NiCl2 (ROH)2 (R= CHMeCH2NMe2).
Hubert-Pfalzgraf LG, et al.
Polyhedron, 16(24), 4197-4203 (1997)
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