371130

1,4-Diisocyanatobutane

97.0%

• Sinonimo/i: Tetramethylene diisocyanate
• Formula condensata: OCN(CH₂)₄NCO
• Numero CAS: 4538-37-8
• Peso molecolare: 140.14
• Beilstein: 1756894
• Numero MDL: MFCD00075559
• Codice UNSPSC: 12162002
• ID PubChem: 24863093
• NACRES: NA.23

Proprietà

• Livello qualitativo: 200
• Saggio: 97.0%
• Stato: liquid
• P. ebollizione: 102-104 °C/14 mmHg (lit.)
• Densità: 1.105 g/mL at 25 °C (lit.)
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: O=C=NCCCCN=C=O
• InChI: 1S/C6H8N2O2/c9-5-7-3-1-2-4-8-6-10/h1-4H2; OVBFMUAFNIIQAL-UHFFFAOYSA-N

Descrizione

Descrizione generale

1,4-Diisocyanatobutane is a highly reactive compound with two isocyanate (-NCO) groups separated by a butane chain. It can undergo reactions such as urethane formation, crosslinking, and chain extension. It is widely used as a building block to synthesize polyurethane-based materials with excellent flexibility, impact resistance, and mechanical properties, making them useful in tissue engineering, contact lenses, biocompatible coatings, adhesives, foams, elastomers, and sealants.

Applicazioni

1,4-Diisocyanatobutanecan be used in the following fields:

Tissue engineering -As a precursor to synthesize polyurethane composites which can be used as 3D scaffolds for tissue engineering,

Contact lenses- As a cross-linking agent to prepare inorganic-organic hydrogel contact lenses for high refractive index ocular refractive correction biomaterial,

Controlled drug delivery- As a chain extender to synthesize segmented polyurethanes for redox-sensitive controlled drug release systems.

Informazioni sulla sicurezza

• Pittogrammi: GHS08,GHS07
• Avvertenze: Danger
• Indicazioni di pericolo: H302 + H312 + H332,H315,H317,H319,H334,H335
• Consigli di prudenza: P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P305 + P351 + P338
• Classi di pericolo: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Organi bersaglio: Respiratory system
• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): 222.8 °F - closed cup
• Punto d’infiammabilità (°C): 106 °C - closed cup
• Dispositivi di protezione individuale: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter