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Key Documents

320137

Sigma-Aldrich

Acrylonitrile

≥99%, contains 35-45 ppm monomethyl ether hydroquinone as inhibitor

Sinonimo/i:

Vinyl cyanide

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About This Item

Formula condensata:
CH2=CHCN
Numero CAS:
Peso molecolare:
53.06
Beilstein:
605310
Numero CE:
Numero MDL:
Codice UNSPSC:
12162002
ID PubChem:
NACRES:
NA.23

Densità del vapore

1.83 (vs air)

Livello qualitativo

Tensione di vapore

86 mmHg ( 20 °C)

Saggio

≥99%

Forma fisica

liquid

Temp. autoaccensione

897 °F

contiene

35-45 ppm monomethyl ether hydroquinone as inhibitor

Limite di esplosione

17 %

Indice di rifrazione

n20/D 1.391 (lit.)

P. eboll.

77 °C (lit.)

Punto di fusione

−83 °C (lit.)

Stringa SMILE

C=CC#N

InChI

1S/C3H3N/c1-2-3-4/h2H,1H2
NLHHRLWOUZZQLW-UHFFFAOYSA-N

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Applicazioni

Acrylonitrile is used in the manufacture of acrylic fibers, resins (acrylonitrile butadiene-styrene, styrene-acrylonitrile and others) and nitrile rubbers (butadiene-acrylonitrile).

Azioni biochim/fisiol

An industrial carcinogen that is a multisite carcinogen in rats and possibly carcinogenic to humans.

Avvertenze

Danger

Classi di pericolo

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Carc. 1B - Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2 - Skin Sens. 1B - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

3 - Flammable liquids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

23.0 °F - closed cup

Punto d’infiammabilità (°C)

-5 °C - closed cup

Dispositivi di protezione individuale

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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Certificati d'analisi (COA)

Lot/Batch Number

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R A Woutersen
Scandinavian journal of work, environment & health, 24 Suppl 2, 5-9 (1998-08-26)
Acrylonitrile is a monomer used extensively as a raw material in the manufacturing of acrylic fibers, plastics, synthetic rubbers, and acrylamide. It has been classified as a probable human carcinogen according to the results of numerous chronic rat bioassays. The
R Thier et al.
Archives of toxicology, 74(4-5), 184-189 (2000-08-26)
The high acute toxicity of acrylonitrile may be a result of its intrinsic biological reactivity or of its metabolite cyanide. Intravenous N-acetylcysteine has been recommended for treatment of accidental intoxications in acrylonitrile workers, but such recommendations vary internationally. Acrylonitrile is
N A Esmen
Scandinavian journal of work, environment & health, 24 Suppl 2, 63-70 (1998-08-26)
The reconstruction of worker exposures has been the mainstay of modem industrial epidemiologic studies. In most cases, the researchers are faced with the difficult dilemma created by the scarcity of the exposure measurement data vis-à-vis the demands for refined quantification.
Acrylonitrile and human cancer--an overview.
D Coggon et al.
Scandinavian journal of work, environment & health, 24 Suppl 2, 81-82 (1998-08-26)
J Whysner et al.
Regulatory toxicology and pharmacology : RTP, 27(3), 217-239 (1998-08-07)
Acrylonitrile (ACN) exposure is associated with tumors in rat brain, Zymbal gland, and mammary gland. Adducts affecting base pairing were formed in isolated DNA exposed in vitro to the ACN metabolite cyanoethylene oxide (CNEO). DNA from liver, which is not

Articoli

RAFT (Reversible Addition Fragmentation chain Transfer) polymerization is a reversible deactivation radical polymerization (RDRP) and one of the more versatile methods for providing living characteristics to radical polymerization.

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