262021

Di-tert-butylsilyl bis(trifluoromethanesulfonate)

97%

• Sinonimo/i: DTBS ditriflate, Di-tert-butylsilyl ditriflate, Trifluoromethanesulfonic acid di-tert-butylsilylene ester
• Formula condensata: (CF₃SO₃)₂Si[C(CH₃)₃]₂
• Numero CAS: 85272-31-7
• Peso molecolare: 440.45
• Beilstein: 3569211
• Numero MDL: MFCD00010581
• Codice UNSPSC: 12352302
• ID PubChem: 24855853
• NACRES: NA.22

Proprietà

• Livello qualitativo: 200
• Saggio: 97%
• Forma fisica: liquid
• Indice di rifrazione: n20/D 1.398 (lit.)
• P. eboll.: 73-75 °C/0.35 mmHg (lit.)
• Densità: 1.352 g/mL at 25 °C (lit.)
• Stringa SMILE: CC(C)(C)[Si](OS(=O)(=O)C(F)(F)F)(OS(=O)(=O)C(F)(F)F)C(C)(C)C
• InChI: 1S/C10H18F6O6S2Si/c1-7(2,3)25(8(4,5)6,21-23(17,18)9(11,12)13)22-24(19,20)10(14,15)16/h1-6H3; HUHKPYLEVGCJTG-UHFFFAOYSA-N

Descrizione

Descrizione generale

Di-tert-butylsilyl bis(trifluoromethanesulfonate), also known as di-tert-butylsilyl ditriflate, that easily reacts with hydroxylic solvents. It is commonly used as a protecting group for diols in oligonucleotide synthesis.

Applicazioni

Di-tert-butylsilyl bis(trifluoromethanesulfonate) is used:

• As a Boekelheide promoter to synthesize pyrrolidines and piperidines via intramolecular cyclization.
• As a protecting group reagent for 1,3-diols used recently in a synthesis of N-homoceramides.
• For selective α-galactosylation in the synthesis of α-galactosyl ceramides.

Informazioni sulla sicurezza

• Pittogrammi: GHS05
• Avvertenze: Danger
• Indicazioni di pericolo: H314
• Consigli di prudenza: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• Classi di pericolo: Skin Corr. 1B
• Codice della classe di stoccaggio: 8A - Combustible corrosive hazardous materials
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): 195.8 °F - closed cup
• Punto d’infiammabilità (°C): 91 °C - closed cup
• Dispositivi di protezione individuale: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter