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109924

Sigma-Aldrich

3-Hydroxypropionitrile

97%

Sinonimo/i:

2-Cyanoethanol, Ethylene cyanohydrin, Hydracrylonitrile

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About This Item

Formula condensata:
HOCH2CH2CN
Numero CAS:
Peso molecolare:
71.08
Beilstein:
635773
Numero MDL:
Codice UNSPSC:
12352100
ID PubChem:
NACRES:
NA.22

Densità del vapore

2.5 (vs air)

Livello qualitativo

Tensione di vapore

<0.1 mmHg ( 20 °C)

Saggio

97%

Temp. autoaccensione

922 °F

Limite di esplosione

12.1 %

Indice di rifrazione

n20/D 1.425 (lit.)

P. ebollizione

228 °C (lit.)

Punto di fusione

−46 °C (lit.)

Densità

1.04 g/mL at 25 °C (lit.)

Gruppo funzionale

hydroxyl
nitrile

Stringa SMILE

OCCC#N

InChI

1S/C3H5NO/c4-2-1-3-5/h5H,1,3H2
WSGYTJNNHPZFKR-UHFFFAOYSA-N

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Descrizione generale

3-Hydroxypropionitrile, at low 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) surface excesses, has the phospholipid oriented with the polar headgroups pointing out of the solution.

3-Hydroxypropionitrile serves as an intermediate through nucleophilic addition or hydrogenation to synthesize heterocyclic rings, mercaptopropanoic acid, or cyclophosphamide.

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

235.4 °F - closed cup

Punto d’infiammabilità (°C)

113 °C - closed cup

Dispositivi di protezione individuale

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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Certificati d'analisi (COA)

Lot/Batch Number

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Hartwig Pohl et al.
Langmuir : the ACS journal of surfaces and colloids, 26(4), 2473-2476 (2009-11-20)
Phospholipids are a main component of cell membranes. Therefore, the experimental investigation of the self-organization of phospholipids is of great interest. Here we present results concerning the orientation of the phospholipid 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) at the surface of the polar solvents
M Duverger-Van Bogaert et al.
Toxicology letters, 7(4-5), 311-319 (1981-02-01)
The mutagenicity of acrylonitrile (ACN) was tested with Salmonella typhimurium TA1530 after a preincubation period of the chemical with a rat liver post-mitochondrial fraction in liquid medium. Several pretreatments were applied to the animals before the preparation of the liver
M Lambotte-Vandepaer et al.
Toxicology letters, 7(4-5), 321-327 (1981-02-01)
Urines collected from rats injected with acrylonitrile (ACN) were mutagenic towards Salmonella typhimurium TA1530; this activity was reduced when the animals were pretreated by pyrazole (inhibitor of alcohol dehydrogenase) and suppressed after pretreatment either by CoCl2 and SKF 525-A (inhibitors
Kid Törnquist et al.
European journal of pharmacology, 453(1), 1-11 (2002-10-24)
Sphingolipid derivatives cause diverse effects towards the regulation of intracellular free Ca(2+) concentrations ([Ca(2+)](i)) in a multitude of nonexcitable cells. In the present investigation, the effect of C-8 ceramide-1-(2-cyanoethyl) phosphate (C1CP) on store-operated Ca(2+) (SOC) entry was investigated. C1CP evoked
Ewa Radzikowska et al.
Organic & biomolecular chemistry, 13(1), 269-276 (2014-11-05)
Chimeric oligonucleotides containing phosphodiester and phosphorothioate linkages have been obtained using the solid phase synthesis. The oligonucleotide parts possessing natural internucleotide phosphate bonds were assembled using commercially available nucleoside 3'-O-(2-cyanoethyl-N,N-diisopropylamino)phosphoramidites 7 whereas the phosphorothioate segment was built using nucleoside 3'-O-(2-thio-1,3,2-oxathiaphospholanes)

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