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Merck

Z2125

Sigma-Aldrich

玉米烯酮

fungal mycotoxin

别名:

F-2毒素

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About This Item

经验公式(希尔记法):
C18H22O5
CAS号:
分子量:
318.36
Beilstein:
1350216
MDL號碼:
分類程式碼代碼:
12191503
PubChem物質ID:
NACRES:
NA.77

品質等級

儲存溫度

−20°C

SMILES 字串

C[C@H]1CCCC(=O)CCC\C=C\c2cc(O)cc(O)c2C(=O)O1

InChI

1S/C18H22O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h3,7,10-12,20-21H,2,4-6,8-9H2,1H3/b7-3+/t12-/m0/s1

InChI 密鑰

MBMQEIFVQACCCH-QBODLPLBSA-N

基因資訊

mouse ... Esr1(13982)

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生化/生理作用

玉米赤霉烯酮,一种从 镰刀菌中获得的真菌霉菌毒素,可结合雌激素受体(ER)并在新生大鼠中具有向子宫性。它是动物和人类食物谷物中常见的污染物,并且发挥调节/破坏动物和可能人的内分泌功能中雌激素活性。

象形圖

Health hazardCorrosion

訊號詞

Danger

危險聲明

危險分類

Eye Dam. 1 - Repr. 2 - Skin Corr. 1B

儲存類別代碼

8A - Combustible corrosive hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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H Leffers et al.
Human reproduction (Oxford, England), 16(5), 1037-1045 (2001-05-02)
We have compared the oestrogenic potency of the synthetic oestrogen Zeranol, used as a growth promoter in meat production, and five related compounds, with the potency of 17beta-oestradiol, diethylstilboestrol (DES), genistein, and Bisphenol-A. The potency was assayed by analysing differences
D M Sheehan et al.
Teratology, 29(3), 383-392 (1984-06-01)
Fusarium sp. contaminated feedstuffs elicit adverse estrogenic effects in several commercially important animal species via the mycotoxin zearalenone. An estrogenically active synthetic derivative, zearalanol, is used as an anabolic agent in cattle. Since estrogens can irreversibly alter target tissue development
Katarzyna Cieplińska et al.
Toxins, 11(5) (2019-05-30)
Zearalenone is a frequent contaminant of cereals and their by-products in regions with a temperate climate. This toxic molecule is produced naturally by Fusarium fungi in crops. The aim of this study was to determine the influence of low zearalenone
Kazimierz Obremski et al.
Toxins, 12(6) (2020-05-31)
The aim of the present study was to determine the effect of zearalenone (ZEN), administered per os to gilts at doses equivalent to 50%, 100%, and 150% of no-observed-adverse-effect level (NOAEL) values for 14, 28, and 42 days during weaning
Cristina Juan et al.
Food chemistry, 134(4), 2389-2397 (2013-02-28)
Although analytical methods have been already reported for legislated mycotoxins as trichothecenes and zearalenone (ZON) separately, we describe the optimization of a simple and rapid multimycotoxin method for the determination of a total of 12 mycotoxins simultaneously, nine trichothecenes (NIV

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