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重組細胞
expressed in baculovirus infected Sf9 cells
產品線
PRECISIO® Kinase
化驗
≥70% (SDS-PAGE)
形狀
buffered aqueous glycerol solution
比活性
11.9-16.1 nmol/min·mg
分子量
~72 kDa
NCBI登錄號
運輸包裝
dry ice
儲存溫度
−70°C
基因資訊
human ... STK32B(55351)
一般說明
STK32B or YANK2 is a serine/threonine protein kinase that contains motif for binding metal ions and nucleotides and the gene for STK32B is highly conserved among various species. STK32B has been associated with isolated cleft lip with or without cleft palate and cleft palate which are among the most common human birth defects of oral cleft cases. Long interspersed nuclear element-1 (LINE-1 or L1) mediated deletion of STK32B gene is observed in patients with Ellis-van Creveld syndrome with borderline intelligence.
外觀
Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
準備報告
after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles
法律資訊
PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Samia A Temtamy et al.
Human mutation, 29(7), 931-938 (2008-05-06)
Previous work has shown Ellis-van Creveld (EvC) patients with mutations either in both alleles of EVC or in both alleles of EVC2. We now report affected individuals with the two genes inactivated on each allele. In a consanguineous pedigree diagnosed
Roxann G Ingersoll et al.
European journal of human genetics : EJHG, 18(6), 726-732 (2010-01-21)
Isolated cleft lip with or without cleft palate and cleft palate are among the most common human birth defects. Several candidate gene studies on MSX1 have shown significant association between markers in MSX1 and risk of oral clefts, and re-sequencing
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