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Merck

73577

Supelco

野黄芩苷

analytical standard

别名:

4′,5,6,7-四羟基黄酮7-葡萄糖醛酸, 5,6-二羟基-2-(4-羟基苯基)-4-氧代-4H-1-苯并吡喃-7-基-β-D-吡喃葡萄糖苷, 7-(β-D-葡糖甘露糖基氧基)-5,6-二羟基-2-(4-羟基苯基)-4H-1-苯并吡喃- 4-酮, 灯盏花素, 野黄芩素-7-O-β-D-葡萄糖苷

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About This Item

经验公式(希尔记法):
C21H18O12
CAS号:
分子量:
462.36
Beilstein:
71779
MDL號碼:
分類程式碼代碼:
85151701
PubChem物質ID:
NACRES:
NA.24

等級

analytical standard

品質等級

化驗

≥98.0% (HPLC)

儲存期限

limited shelf life, expiry date on the label

技術

HPLC: suitable
gas chromatography (GC): suitable

應用

food and beverages

格式

neat

儲存溫度

2-8°C

SMILES 字串

O[C@@H]1[C@@H](O)[C@@H](O[C@@H]([C@H]1O)C(O)=O)Oc2cc3OC(=CC(=O)c3c(O)c2O)c4ccc(O)cc4

InChI

1S/C21H18O12/c22-8-3-1-7(2-4-8)10-5-9(23)13-11(31-10)6-12(14(24)15(13)25)32-21-18(28)16(26)17(27)19(33-21)20(29)30/h1-6,16-19,21-22,24-28H,(H,29,30)/t16-,17-,18+,19-,21+/m0/s1

InChI 密鑰

DJSISFGPUUYILV-ZFORQUDYSA-N

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一般說明

野黄芩甙是一种黄酮类葡萄糖醛酸苷,是灯盏花素的一种活性成分。它可广泛用于治疗脑梗死、冠心病和心绞痛。

應用

有关合适仪器技术的更多信息,请参考产品分析证书。如需进一步支持,请联系技术服务。
野黄芩苷可作为分析参考标准品,通过不同的色谱技术对血浆样品中的分析物进行定量。

生化/生理作用

野黄芩苷是一种类黄酮,具有多种心脏和神经保护作用。在大鼠心肌梗死模型中,野黄芩苷可以抑制p38活性、ERK磷酸化和TGF-β表达和纤维化。在脑缺血再灌注模型中,该化合物通过增加eNOS表达,同时抑制iNOS的诱导,进而减少梗塞体积和神经功能缺损。

包裝

无底玻璃瓶。内含物在插入的融合锥体内。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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