SML3583
PF-04634817 succinate
≥98% (HPLC)
别名:
1,5-Anhydro-2,3-dideoxy-4-O-methyl-3-[[(1R,3S)-3-(1-methylethyl)-3-[[(1S,4S)-5-[6-(trifluoromethyl)-4-pyrimidinyl]-2,5-diazabicyclo[2.2.1]hept-2-yl]carbonyl]cyclopentyl]amino]-D-erythro-pentitol succinate
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About This Item
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品質等級
化驗
≥98% (HPLC)
形狀
powder
顏色
white to beige
溶解度
DMSO: 2 mg/mL, clear
儲存溫度
room temp
SMILES 字串
CO[C@H]1[C@@H](N[C@@H]2CC[C@@](C(N3C[C@@]4([H])N(C5=NC=NC(C(F)(F)F)=C5)C[C@]3([H])C4)=O)(C(C)C)C2)CCOC1
生化／生理作用
Orally available, potent and selective CCR2/5 receptor antagonist
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Identification of Molecular Signatures and Candidate Drugs in Vascular Dementia by Bioinformatics Analyses
Shu J, Wei W, Zhang L
Frontiers in Molecular Neuroscience, 15, 751044-751044 (2022)
Effect of PF-04634817, an Oral CCR2/5 Chemokine Receptor Antagonist, on Albuminuria in Adults with Overt Diabetic Nephropathy
Gale JD, Gilbert S, Blumenthal S, Elliott T, Pergola PE, Goteti K, Scheele W, Perros-Huguet C
Kidney international reports, 3, 1316-1327 (2018)
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