SML0234

Mitiglinide calcium

≥98% (HPLC)

• 别名: (aS,3aR,7aS)-Octahydro-g-oxo-a-(phenylmethyl)-2H-isoindole-2-butanoic acid calcium salt, KAD 1229, Mitiglinide hemicalcium salt, S 21403, [2(S)-cis]-Octahydro-g-oxo-a-(phenylmethyl)-2H-isoindole-2-butanoic acid calclium salt
• 经验公式（希尔记法）: C₁₉H₂₄NO₃·0.5Ca
• CAS号: 145525-41-3
• 分子量: 334.44
• MDL號碼: MFCD09955408
• 分類程式碼代碼: 12352200
• PubChem物質ID: 329825247
• NACRES: NA.77

属性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 光學活性: [α]/D +5 to +9° (c=1, MeOH)
• 儲存條件: desiccated
• 顏色: white to beige
• 溶解度: DMSO: ≥10 mg/mL at warmed to 60 °C
• 儲存溫度: room temp
• SMILES 字串: O=C(C[C@H](Cc1ccccc1)C(=O)O[Ca]OC(=O)[C@H](CC(=O)N2C[C@H]3CCCC[C@H]3C2)Cc4ccccc4)N5C[C@H]6CCCC[C@H]6C5
• InChI: 1S/2C19H25NO3.Ca/c2*21-18(20-12-15-8-4-5-9-16(15)13-20)11-17(19(22)23)10-14-6-2-1-3-7-14;/h2*1-3,6-7,15-17H,4-5,8-13H2,(H,22,23);/q;;+2/p-2/t2*15-,16+,17-;/m00./s1
• InChI 密鑰: PMRVFZXOCRHXFE-FMEJWYFOSA-L

说明

生化／生理作用

Mitiglinide calcium is a highly selective KATP channel antagonist

Mitiglinide is a drug for the treatment of type 2 diabetes. It is a highly selective KATP channel antagonist Mitiglinide is a hypoglycemic agent that closes adenosine triphosphate (ATP)–sensitive potassium channels (KATP channel s) in the pancreatic β-islet cells.

特點和優勢

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable