P7556

Progesterone-Water Soluble

powder, BioReagent, suitable for cell culture

• 别名: Progesterone: HBC complex, Progesterone: methyl-β-cyclodextrin complex
• MDL號碼: MFCD00003658
• 分類程式碼代碼: 12352209
• PubChem物質ID: 57654558
• NACRES: NA.77

属性

• 生物源: synthetic (organic)
• 品質等級: 200
• 產品線: BioReagent
• 形狀: powder
• 濃度: ≥65% (HPLC)
• 技術: cell culture | mammalian: suitable
• 溶解度: H₂O: 25 mg/mL, clear to slightly hazy
• 運輸包裝: ambient
• 儲存溫度: room temp
• SMILES 字串: [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@H](CC[C@@]24[H])C(C)=O
• InChI: 1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1
• InChI 密鑰: RJKFOVLPORLFTN-LEKSSAKUSA-N
• 基因資訊: human ... ABCB1(5243) , AR(367) , CYP2C9(1559) , EBP(10682) , ESR1(2099) , ESR2(2100) , NR3C1(2908) , NR3C2(4306) , PGR(5241) , SERPINA6(866) ; mouse ... Esr1(13982) ; rat ... Ar(24208) , Nr3c1(24413) , Pgr(25154)

说明

一般說明

Progesterone is a steroid hormone secreted by the ovaries.

應用

Progesterone-Water Soluble has been used:

• for in vitro maturation of oocyte complexes
• as a σ1R antagonist to study its effect on sigma 1 receptor
• to study its effect on the differentiation of human multipotent mesenchymal stromal cells (hMSCs) in vitro

This product is not recommended for use in binding assays.

生化／生理作用

Progesterone is a hormone that maintains pregnancy. It is essential for embryo formation, development and survival in almost all mammals. This hormone exhibits its action via progesterone receptor, which is specifically expressed in the endometrial stroma throughout pregnancy. It is known to prevent preterm delivery, when administered intramuscularly. Progesterone also controls gonadotropin secretion, activates sexual behavior and triggers ovarian events leading to ovulation. It stimulates the growth and differentiation of the uterus and prevents uterine contractility.

包裝

Package size based on progesterone content

其他說明

Contains approx. 70 mg progesterone per gram; balance methyl-β-cyclodextrin.

安全信息

• 象形圖: GHS08
• 訊號詞: Danger
• 危險聲明: H351,H360FD,H362
• 防範說明: P202 - P260 - P263 - P264 - P280 - P308 + P313
• 危險分類: Carc. 2 - Lact. - Repr. 1A
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable