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生物源
human
品質等級
重組細胞
expressed in E. coli
化驗
≥98% (SDS-PAGE and HPLC)
形狀
lyophilized powder
效力
0.500-5.000 ng/mL ED50
品質
endotoxin tested
分子量
dimer 37 kDa
包裝
pkg of 10 μg
技術
cell culture | mammalian: suitable
雜質
≤1.000 EU/μg
顏色
white
UniProt登錄號
儲存溫度
−20°C
基因資訊
human ... CSF1(1435)
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一般說明
Macrophage Colony-Stimulating Factor (M-CSF) is a hematopoietic growth factor, which modulates the proliferation, differentiation and functional activation of monocytes. It is produced by fibroblasts, endothelial cells and bone marrow stromal cells. MCSF stimulates the functions of mature monocytes and macrophages.
應用
Macrophage Colony-Stimulating Factor human has been used for the differentiation of bone marrow-derived macrophages (BMDMs) and human monocyte-derived macrophages (MDMs). It has also been used for cell culture.
生化／生理作用
Macrophage colony-stimulating factor (M-CSF) augments many of the physiological functions of macrophages, and support osteoclast differentiation.
其他說明
159 amino acids including N-terminal methionine (each monomer).
外觀
Lyophilized from a sterile filtered buffered solution.
分析報告
The proliferative activity is tested in culture using the cytokine-dependent murine monocytic cell line M-NFS-60 cells.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
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商品
Read article on hematopoietic cytokines and hematopoiesis
Read article on hematopoietic cytokines and hematopoiesis
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