推荐产品
生物源
Escherichia coli (O26:B6)
品質等級
形狀
lyophilized powder
比活性
≥10,000 EU/mg
純化經由
phenol extraction
雜質
<3% Protein (Lowry)
顏色
white to faint yellow
溶解度
water: soluble
運輸包裝
ambient
儲存溫度
2-8°C
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相关类别
一般說明
该产品是来自大肠杆菌血清型 O26:B6的酚提取物。源菌株是ATCC 12795。来自血清型 026的LPS:B6是来自大肠杆菌的唯一 LPS,其在SDS-PAGE 上表现出短链长行为。该 LPS的短链长度接近突变粗糙株 LPS的短链长。该 LPS 血清型(1ug/ml),用于刺激中性粒细胞。
應用
脂多糖(LPS)是革兰氏阴性细菌细胞壁的特征成分。LPS及其脂质A部分通过Toll样受体4(TLR4)刺激先天免疫系统的细胞,TLR4是Toll样受体蛋白家族的成员,该家族可识别常见的病原体相关分子模式(PAMP)。
生化/生理作用
脂多糖(LPS)位于膜的外层,在非包封的菌株中,暴露在细胞表面上。它们有助于外膜的完整性,并保护细胞免受胆汁盐和亲脂性抗生素的影响。
準備報告
产物可溶于水(5mg/ml)或细胞培养基(1mg/ml),产生浑浊的、淡黄色溶液。在经过涡旋和加温至 70-80oC 后,在水溶的盐水中得到更浓缩、但仍然浑浊的溶液(20mg/ml)。脂多糖是在各种溶剂中形成胶束的分子。在水和磷酸盐缓冲盐水中观察到浑浊的溶液。有机溶剂不能提供更澄清的溶液。甲醇产生具有漂浮物的混浊悬浮液,而水产生均匀混浊的溶液。
相關產品
产品编号
说明
价格
訊號詞
Danger
危險聲明
危險分類
Acute Tox. 2 Oral
儲存類別代碼
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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