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品質等級
化驗
≥98% (HPLC)
形狀
oil
顏色
colorless to yellow
溶解度
DMSO: freely soluble
methanol: soluble
起源
Johnson & Johnson
運輸包裝
wet ice
儲存溫度
−20°C
SMILES 字串
CC(C)OC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1CC[C@@H](O)CCc2ccccc2
InChI
1S/C26H40O5/c1-19(2)31-26(30)13-9-4-3-8-12-22-23(25(29)18-24(22)28)17-16-21(27)15-14-20-10-6-5-7-11-20/h3,5-8,10-11,19,21-25,27-29H,4,9,12-18H2,1-2H3/b8-3-/t21-,22+,23+,24-,25+/m0/s1
InChI 密鑰
GGXICVAJURFBLW-CEYXHVGTSA-N
基因資訊
human ... PTGFR(5737)
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應用
拉坦前列素已被用于：
- 制备包含姜黄素纳米颗粒（CUR-NP）的热敏水凝胶，以确定其在氧化应激下对人小梁网（TM）细胞的治疗作用。
- 作为酯类前药用于研究其对小鼠鼠眼表面的作用
- 制备热敏水凝胶用于研究其对控制高眼压症的作用。
生化／生理作用
拉坦前列素是一种强效、选择性前列腺素F2 α类似物受体激动剂。它在角膜中被酯酶水解为拉坦前列素酸的生物活性形式。拉坦前列素在降低眼内压（IOP）方面起一定作用，因此它具有治疗青光眼的疗效。
特點和優勢
该化合物由 Johnson & Johnson 开发。如需浏览其他制药公司开发的化合物和批准的药物/候选药物列表，请点击此处。
訊號詞
Warning
危險聲明
危險分類
Repr. 2
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Faceshields, Gloves, type N95 (US)
其他客户在看
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To clarify the mechanism of prostaglandin (PG) analogue-dependent relaxation in ciliary arteries from wild-type (WT) and prostanoid receptor-deficient mice. The intracellular-free calcium concentration ([Ca(2+)](i)) in isolated WT mouse ciliary arteries was measured by fluorescence photometry. Reduction of [Ca(2+)](i) leading to
A T Fung et al.
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To compare the efficacy and tolerability of latanoprost versus brimonidine in the treatment of open-angle glaucoma, ocular hypertension or normal-tension glaucoma. Systematic review of randomised controlled trials comparing latanoprost and brimondine, identified by searches including Medline, Embase and Cochrane Controlled
Anastasios G P Konstas et al.
The British journal of ophthalmology, 97(12), 1510-1515 (2013-05-18)
To compare 24 h intraocular pressure (IOP) control obtained with preservative free (PF) tafluprost 0.0015% versus branded preservative containing latanoprost 0.005% administered as first choice monotherapy in patients with primary open angle glaucoma (POAG) or ocular hypertension (OHT). This prospective
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