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Merck

C6116

Sigma-Aldrich

(+/-)-氯前列醇钠盐水合物 钠盐 水合物

≥98% (HPLC), powder

别名:

7-[2-[4-(3-氯苯氧基)-3-羟基丁-1-烯基]-3,5-二羟基环戊基]庚-5-烯酸钠 钠盐 水合物

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About This Item

经验公式(希尔记法):
C22H28ClNaO6 · xH2O
CAS号:
分子量:
446.90 (anhydrous basis)
EC號碼:
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

品質等級

化驗

≥98% (HPLC)

形狀

powder

儲存條件

desiccated

顏色

light brown

mp

68-70 °C

溶解度

H2O: >10 mg/mL

儲存溫度

−20°C

SMILES 字串

[Na+].[H]O[H].O[C@@H](COc1cccc(Cl)c1)\C=C\[C@H]2[C@H](O)C[C@H](O)[C@@H]2C\C=C/CCCC([O-])=O

InChI

1S/C22H29ClO6.Na.H2O/c23-15-6-5-7-17(12-15)29-14-16(24)10-11-19-18(20(25)13-21(19)26)8-3-1-2-4-9-22(27)28;;/h1,3,5-7,10-12,16,18-21,24-26H,2,4,8-9,13-14H2,(H,27,28);;1H2/q;+1;/p-1/b3-1-,11-10+;;/t16-,18-,19-,20+,21-;;/m1../s1

InChI 密鑰

ZEQHRVULQBYULU-LPFHDDPUSA-M

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一般說明

氯前列醇是前列腺素F2α(PGF)的合成类似物。 氯前列醇有助于诱导动物发情,并具有子宫收缩作用。氯前列醇会诱发动物流产。

應用

(+/-)-氯前列醇钠盐水合物已用于研究其对小鼠发情同期和子宫发育的影响。

生化/生理作用

氯前列醇是一种有效的FP前列腺素类受体激动剂。
氯前列醇是一种有效的FP前列腺素类受体激动剂。与氟前列醇相比,氯前列醇更有效,但选择性较低。对于EP和TP前列腺素受体,氯前列醇与PGF 的效力相近。它可用于治疗母猪和小母猪的不孕症。

特點和優勢

《受体分类和信号转导》手册的 前列腺素类受体 页面有该化合物的介绍。想要浏览手册的其他页面, 请单击此处

象形圖

Health hazardExclamation mark

訊號詞

Warning

危險分類

Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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