推荐产品
化驗
≥95% (HPLC)
光學活性
[α]/D 26.0 to 36.0°, c = 0.1 in methanol
顏色
pale yellow, oil
溶解度
DMSO: freely soluble
methanol: soluble
起源
Johnson & Johnson
運輸包裝
wet ice
儲存溫度
−20°C
SMILES 字串
O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O)CCc2ccccc2
InChI
1S/C23H34O5/c24-18(13-12-17-8-4-3-5-9-17)14-15-20-19(21(25)16-22(20)26)10-6-1-2-7-11-23(27)28/h1,3-6,8-9,18-22,24-26H,2,7,10-16H2,(H,27,28)/b6-1-/t18-,19+,20+,21-,22+/m0/s1
InChI 密鑰
HNPFPERDNWXAGS-NFVOFSAMSA-N
基因資訊
mouse ... Ptgfr(19220)
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生化/生理作用
Potent, selective FP prostanoid receptor agonist, F-series prostaglandin analog. 200 times as potent as isopropyl ester form.
特點和優勢
This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
包裝
Store tightly sealed, under desiccant.
儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves
Investigative ophthalmology & visual science, 38(13), 2772-2780 (1998-01-07)
To identify matrix metalloproteinases (MMPs) released by ciliary smooth muscle cells in vitro and to determine whether MMP release is altered by exposure to prostaglandins (PGs). Human ciliary smooth muscle cells were grown to confluence in monolayer cultures and treated
Current eye research, 22(3), 198-207 (2001-07-20)
Latanoprost, a prostaglandin F2a analogue and ocular hypotensive agent, alters extracellular matrix and matrix metalloproteinases (MMPs), including MMP-1, within tissues of the uveoscleral outflow pathway. In addition to these tissues, the anterior choroid also is exposed to fluid within the
Rapid metabolic responses to prostaglandins in cultured cells expressing the FP-receptor.
Advances in experimental medicine and biology, 407, 231-236 (1997-01-01)
Effect of prostaglandins A(2), E(1), F(2 alpha)and latanoprost on cultured human iridal melanocytes.
Experimental eye research, 70(1), 113-120 (2000-01-25)
The effect of various prostaglandins on the growth, melanogenesis and dendrification of cultured iridal melanocytes were studied. Iridal melanocytes were isolated and cultured with medium supplemented with cAMP elevating agents and basic fibroblast growth factor (complete medium). The iridal melanocytes
Investigative ophthalmology & visual science, 42(7), 1514-1521 (2001-05-31)
To investigate the effect of prostaglandins (PGs) on the permeability of human sclera in vitro. Twenty-three pairs of human eye bank eyes were studied. Circular pieces of sclera were cultured in low-serum DMEM/F-12 media. Scleral hydration was assessed by measuring
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