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Merck

I6284

Sigma-Aldrich

抗- 人 IgE(ε-特定链) 山羊抗

affinity isolated antibody, lyophilized powder

别名:

Anti Human Ige, Anti-Human IgE - Anti-Human IgE (ε-chain specific) antibody produced in goat, Anti-Human Ige

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.46

生物源

goat

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

secondary antibodies

無性繁殖

polyclonal

形狀

lyophilized powder

物種活性

human

技術

Ouchterlony double diffusion: suitable

儲存溫度

2-8°C

目標翻譯後修改

unmodified

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一般說明

IgE是一类只能由哺乳动物生产的免疫球蛋白。IgE 是由肥大细胞出于对过敏原的响应而分泌,对于针对寄生虫的免疫十分重要。它也是过敏反应或一型高血压的病理生理学中最重要的因子。当与纯化人IgA、IgG、IgM、本周氏κ和本周氏κ蛋白共同测试时,该产品只和人IgE反应。通过免疫电泳鉴定免疫球蛋白及其纯度。

免疫原

纯化的人 IgE(骨髓瘤)

應用

抗人 IgE(ε 链特异性)抗体可用作各种免疫测定中的对照。

外觀

冻干品,来自 0.01 mM 磷酸钠,0.015 mM 氯化钠,pH 7.2。

重構

用 0.135 M 氯化钠重构,得到 1 mg/mL 的抗体溶液。

免責聲明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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访问文档库

Shiteng Duan et al.
The Journal of clinical investigation, 129(3), 1387-1401 (2019-01-16)
Allergen immunotherapy for patients with allergies begins with weekly escalating doses of allergen under medical supervision to monitor and treat IgE mast cell-mediated anaphylaxis. There is currently no treatment to safely desensitize mast cells to enable robust allergen immunotherapy with
Bettina Wedi et al.
Allergy, 75(9), 2229-2242 (2020-02-01)
Mas-related G protein-coupled receptor X2 (MRGPRX2) is regarded as a mast cell-specific receptor mediating non-IgE-dependent activation. We aimed to investigate whether human basophils and eosinophils express functional MRGPRX2. Flow cytometry, immunocytochemistry, immunofluorescence, Western blot, and RT-PCR were performed in highly
Stephen J Galli et al.
Nature medicine, 18(5), 693-704 (2012-05-09)
Immunoglobulin E (IgE) antibodies and mast cells have been so convincingly linked to the pathophysiology of anaphylaxis and other acute allergic reactions that it can be difficult to think of them in other contexts. However, a large body of evidence
Jie Zhao et al.
mAbs, 11(5), 837-847 (2019-04-06)
Asthma is characterized by airway hyperresponsiveness and inflammation, as well as underlying structural changes to the airways. Interleukin-4 (IL-4) is a key T-helper type 2 (Th2) cytokine that plays important roles in the pathogenesis of atopic and eosinophilic asthma. We
Minjae Kim et al.
Journal of immunology (Baltimore, Md. : 1950), 208(3), 772-779 (2022-01-14)
Human IgE is useful for immunological assays, such as sensitization of FcεRI-positive cells and IgE measurement. In this study, we report the development of a recombinant Ig fragment, designated IgCw-γεκ, as an alternative reagent to human IgE. IgCw-γεκ (∼130 kDa)

商品

Antibody-based serology tests are useful in identifying subjects with an adaptive immune response to the SARS-CoV-2 virus. Anti-human immunoglobulin antibodies allow for quick and simple, yet reliable assays with easy readouts and can also be adapted for high-throughput screening.

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