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H3631

Sigma-Aldrich

透明质酸酶 来源于牛睾丸

Type VI-S, lyophilized powder, 3,000-15,000 units/mg solid

别名:

玻璃糖醛酸酶, 玻璃酸酶

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About This Item

CAS号:
37326-33-3
EC 号:
3.2.1.35 (BRENDA, IUBMB)
EC號碼:
253-464-3
MDL號碼:
MFCD00131351
分類程式碼代碼:
12352204
NACRES:
NA.54

生物源

bovine testis

品質等級

200

共軛

conjugate (Glucosaminoglycan)

種類

Type VI-S

形狀

lyophilized powder

比活性

3,000-15,000 units/mg solid

分子量

~55 kDa (four subunits of 14 kDa each)

UniProt登錄號

Q5E985
Q8SQG8

相關疾病

cancer

儲存溫度

−20°C

基因資訊

cow ... HYAL1(515397) , HYAL2(281838)

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相关类别

生化／生理作用

这些酶可随机裂解透明质酸、软骨素和硫酸软骨素中的 β-N-乙酰己糖胺-[1→4] 糖苷键。
透明质酸酶可降解透明质酸，并已发现可在癌症进展期间会被不适当地调节。

單位定義

在 37 ºC、pH 5.35 条件下，一单位每分钟可降解 0.75 μg 多糖透明质酸（通过比浊吸光度测量(λ: 600nm)，与 BSA 复合 45 分钟后测量）。

準備報告

色谱纯化产品

其他說明

更多关于复杂碳水化合物分析酶的信息，请见www.sigma-aldrich.com/enzymeexplorer

象形圖

Health hazard
GHS08

訊號詞

Danger

危險聲明

H334

防範說明

P261 - P284 - P501

危險分類

Resp. Sens. 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
SLBZ0772
SLBZ3166
SLBV2044
SLBQ5073V
SLBJ9451V

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Tongcui Ma et al.
eLife, 11 (2022-07-06)
High-parameter single-cell phenotyping has enabled in-depth classification and interrogation of immune cells, but to date has not allowed for glycan characterization. Here, we develop CyTOF-Lec as an approach to simultaneously characterize many protein and glycan features of human immune cells
Dong-Ru Ho et al.
International journal of urology : official journal of the Japanese Urological Association, 18(7), 525-531 (2011-05-25)
To investigate how hyaluronic acid (HA) affects nerve growth factor (NGF) production and bladder overactivity in a cyclophosphamide (CYP)-induced cystitis rat model. Female Sprague-Dawley rats received three intermittent intraperitoneal injections of CYP (75 mg/kg) or saline. Before or after CYP injection
Tongcui Ma et al.
eLife, 9 (2020-05-27)
The female reproductive tract (FRT) is the most common site of infection during HIV transmission to women, but viral remodeling complicates characterization of cells targeted for infection. Here, we report extensive phenotypic analyses of HIV-infected endometrial cells by CyTOF, and
Shared decision making, thrombotic thrombocytopenic purpura, and caplacizumab.
Senthil Sukumar et al.
American journal of hematology, 95(4), E76-E77 (2020-01-03)
Annemiek Dickhout et al.
International journal of molecular sciences, 22(14) (2021-07-25)
The chemokines CCL5 and CXCL4 are deposited by platelets onto endothelial cells, inducing monocyte arrest. Here, the fate of CCL5 and CXCL4 after endothelial deposition was investigated. Human umbilical vein endothelial cells (HUVECs) and EA.hy926 cells were incubated with CCL5
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