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Merck

G7132

Sigma-Aldrich

甘胆酸钠 水合物

≥95% (TLC)

别名:

3α,7α,12α-三羟基-5β-胆烷-24-酸 N-(羧甲基)酰胺 钠盐, N-(3α,7α,12α-三羟基-24-氧代胆碱-24-基)甘氨酸 钠盐, 甘氨胆酸 钠盐, 甘氨胆酸 钠盐 水合物

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About This Item

线性分子式:
C26H42NO6Na · xH2O
分子量:
487.60 (anhydrous basis)
Beilstein:
3854517
EC號碼:
MDL號碼:
分類程式碼代碼:
12161900
PubChem物質ID:
NACRES:
NA.25

描述

anionic

品質等級

化驗

≥95% (TLC)

分子量

micellar avg mol wt 900(lit.)

凝集数

1.9

CMC

13 mM (20-25°C)(lit.)

mp

210-215 °C (subl.) (lit.)

SMILES 字串

[Na+].[H]O[H].[H][C@@]12C[C@H](O)CC[C@]1(C)[C@@]3([H])C[C@H](O)[C@]4(C)[C@H](CC[C@@]4([H])[C@]3([H])[C@H](O)C2)[C@H](C)CCC(=O)NCC([O-])=O

InChI

1S/C26H43NO6.Na.H2O/c1-14(4-7-22(31)27-13-23(32)33)17-5-6-18-24-19(12-21(30)26(17,18)3)25(2)9-8-16(28)10-15(25)11-20(24)29;;/h14-21,24,28-30H,4-13H2,1-3H3,(H,27,31)(H,32,33);;1H2/q;+1;/p-1/t14-,15+,16-,17-,18+,19+,20-,21+,24+,25+,26-;;/m1../s1

InChI 密鑰

YWROUPFMHKARON-HJRQWJHVSA-M

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一般說明

甘胆酸钠水合物是一种共轭胆盐和离子型生物洗涤剂。

應用

在一项研究中,使用甘胆酸钠水合物通过荧光法和酶法评估血清总胆汁酸。 也用于研究其对睾酮胶束形成和增溶的影响。

生化/生理作用

胆盐

準備報告

该产品由天然胆酸(产品号C1129)合成制备而成。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Micelle formation and testosterone solubilization by sodium glycocholate.
L Martis et al.
Journal of pharmaceutical sciences, 61(11), 1757-1761 (1972-11-01)
Mari Araki et al.
Journal of biochemistry, 160(5), 269-279 (2016-11-02)
DDHD2 has been reported to exhibit phospholipase A
Feilong Sun et al.
Colloids and surfaces. B, Biointerfaces, 170, 521-528 (2018-07-04)
Poorly soluble vitamin K cannot be absorbed by patients suffering from cholestasis due to extremely low level of bile salts in the intestine. A formulation of vitamin K including glycocholic acid (i.e. Konakion® MM), does not increase bioavailability because it
Monalisa Mohapatra et al.
Langmuir : the ACS journal of surfaces and colloids, 27(22), 13461-13467 (2011-10-07)
The interaction of submicellar concentrations of various physiologically important unconjugated [sodium deoxycholate (NaDC), sodium cholate (NaC)] and conjugated [sodium glycodeoxycholate (NaGDC), sodium glycocholate (NaGC), sodium taurodeoxycholate (NaTDC), sodium taurocholate (NaTC)] bile salts with dipalmitoylphosphatidylcholine (DPPC) and dimyristoylphosphatidylcholine (DMPC) small unilamellar
Ferenc Zsila et al.
International journal of biological macromolecules, 129, 50-60 (2019-02-05)
The human antimicrobial and immunomodulatory peptide LL-37 is ubiquitously expressed and secreted by epithelial cells of mucosal surfaces including the gastrointestinal tract, the primary absorption site of orally administered drugs and food components. Besides antimicrobial properties, LL-37 also contributes to

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Today, diverse studies report the benefits of probiotics, such as inhibitory effects on pathogens, aid in the management or prevention of chronic intestinal inflammatory diseases or atopic syndromes, and support to the immune system. Potential beneficial applications abound, researchers continue to evaluate the effictiveness and clarify the mechanisms of action of probiotics.

实验方案

To standardize a procedure for the determination of the enzymatic assay of choloylglycine hydrolase.

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