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Merck

T7515

Sigma-Aldrich

牛磺石胆酸钠

别名:

3α-羟基-5β-胆烷-24-羧酸-N-(2-磺乙基)酰胺, 牛磺石胆酸 钠盐

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About This Item

线性分子式:
C26H44NO5SNa
CAS号:
分子量:
505.69
分類程式碼代碼:
12161900
PubChem物質ID:
NACRES:
NA.25

描述

anionic

化驗

≥97.0% (TLC)

分子量

505.69 g/mol

應用

detection

SMILES 字串

C[C@H](CCC(NCCS(=O)(O)=O)=O)[C@@]1([H])CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C.[Na]

InChI

1S/C26H45NO5S.Na.H/c1-17(4-9-24(29)27-14-15-33(30,31)32)21-7-8-22-20-6-5-18-16-19(28)10-12-25(18,2)23(20)11-13-26(21,22)3;;/h17-23,28H,4-16H2,1-3H3,(H,27,29)(H,30,31,32);;/t17-,18-,19-,20+,21-,22+,23+,25+,26-;;/m1../s1

InChI 密鑰

CMXYYIRKQPXCIE-RLHFEMFKSA-N

一般說明

牛磺胆酸钠是一种具有洗涤剂特性的胆汁盐,该特性使其能够溶解不溶性脂质。

應用

牛磺胆酸钠已被用于评估石油烃残留物的胃肠道吸附的控制因素。 它还被用于研究诱导胆汁淤积的大鼠中Na+、K+-腺苷三磷酸酶(Na+、K+-ATP酶)活性的降低。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Sohail Z Husain et al.
American journal of physiology. Gastrointestinal and liver physiology, 302(12), G1423-G1433 (2012-04-21)
Biliary pancreatitis is the most common etiology for acute pancreatitis, yet its pathophysiological mechanism remains unclear. Ca(2+) signals generated within the pancreatic acinar cell initiate the early phase of pancreatitis, and bile acids can elicit anomalous acinar cell intracellular Ca(2+)
Xuejun Zhang et al.
The journal of physical chemistry. B, 115(49), 14445-14449 (2011-11-15)
Stimuli-responsive organic tubes are an attractive supramolecular assembly which has potential applications as a controlled release vehicle. We synthesize a smart organic tube by the coassembly of lithocholic acid (LCA) and taurolithocholic acid (TLCA) in aqueous solution. The coassembled LCA/TLCA
Kjell B Døving et al.
The Journal of experimental biology, 214(Pt 1), 80-87 (2010-12-15)
In the present study, we exposed the olfactory epithelia of crucian carp, Carassius carassius, and brown trout, Salmo trutta, to dextran coupled with Alexa dyes together with odorants. Dye uptake was severely reduced after pre-exposure to nocodazole, an inhibitor of
Hoi-Ying N Holman et al.
Environmental science & technology, 36(6), 1281-1286 (2002-04-12)
Petroleum hydrocarbon residues in weathered soils may pose risks to humans through the ingestion pathway. To understand the factors controlling their gastrointestinal (GI) absorption, a newly developed experimental extraction protocol was used to model the GI solubility of total petroleum
J Reichen et al.
Experientia, 35(9), 1186-1188 (1979-09-15)
Na +, K + -adenosinetriphosphatase (Na +, K + -ATPase) activity was decreased in liver plasma membranes from rats in which cholestasis had been induced by i.v. administration of sodium taurolithocholate (5 mumoles/100 g b. wt). Incubation of liver plasma

实验方案

This method is particularly useful in research into the role of individual bile acids as signaling molecules; suitable for clinical laboratories to investigate potential mechanisms linked to gut hormone profiles and glycemic control.

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