所有图片(4)
About This Item
经验公式(希尔记法):
C5H3FN2O4 · xH2O
CAS号:
分子量:
174.09 (anhydrous basis)
EC號碼:
MDL號碼:
分類程式碼代碼:
12352204
PubChem物質ID:
NACRES:
NA.32
推荐产品
生物源
synthetic
品質等級
化驗
≥98%
形狀
powder
技術
cell culture | plant: suitable
mp
278 °C (dec.) (lit.)
溶解度
4 M NH4OH: 50 mg/mL, clear, colorless to light yellow
儲存溫度
−20°C
SMILES 字串
OC(C(NC(N1)=O)=C(F)C1=O)=O.[H]O[H]
InChI
1S/C5H3FN2O4.H2O/c6-1-2(4(10)11)7-5(12)8-3(1)9;/h(H,10,11)(H2,7,8,9,12);1H2
InChI 密鑰
LODRRYMGPWQCTR-UHFFFAOYSA-N
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應用
5-氟乳清酸水合物也已用作反向筛选剂,用于筛选乳酸乳球菌(多种)肽酶敲除突变体和白色念珠菌。它已用于合成5-氟乳清苷5′-单磷酸(FOMP)。
可用于选择酿酒酵母的乳清苷-5′-磷酸脱羧酶突变体。
生化/生理作用
5-氟乳清酸是哺乳动物中rRNA合成的选择性抑制剂。
訊號詞
Warning
危險分類
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
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Wood B M, et al.
Biochemistry, 48(24), 5510-5517 (2009)
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Genetics, 212(4), 1121-1132 (2019-05-31)
The diploid budding yeast Candida albicans harbors unique CENPA-rich 3- to 5-kb regions that form the centromere (CEN) core on each of its eight chromosomes. The epigenetic nature of these CENs does not permit the stabilization of a functional kinetochore
Jiaxin Gao et al.
Nature communications, 9(1), 4495-4495 (2018-10-31)
Fungal infections by drug-resistant Candida albicans pose a global public health threat. However, the pathogen's diploid genome greatly hinders genome-wide investigations of resistance mechanisms. Here, we develop an efficient piggyBac transposon-mediated mutagenesis system using stable haploid C. albicans to conduct
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