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Merck

U1128

Sigma-Aldrich

尿嘧啶

BioReagent, suitable for cell culture

别名:

2,4(1H,3H)-嘧啶二酮, 2,4-二羟基嘧啶, 灭胞素

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About This Item

经验公式(希尔记法):
C4H4N2O2
CAS号:
分子量:
112.09
Beilstein:
507828
EC號碼:
MDL號碼:
分類程式碼代碼:
12352207
PubChem物質ID:
NACRES:
NA.75

生物源

synthetic (organic)

品質等級

產品線

BioReagent

化驗

≥99% (HPLC)

形狀

powder

技術

cell culture | mammalian: suitable

mp

>300 °C (lit.)

溶解度

1 M NaOH: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

儲存溫度

room temp

SMILES 字串

O=C1NC=CC(=O)N1

InChI

1S/C4H4N2O2/c7-3-1-2-5-4(8)6-3/h1-2H,(H2,5,6,7,8)

InChI 密鑰

ISAKRJDGNUQOIC-UHFFFAOYSA-N

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一般說明

尿嘧啶属于嘧啶碱基家族。它是天然存在的,是RNA重要而活跃的一部分。

應用

尿嘧啶已用作完全合成培养基1×、合成完全葡萄糖基酵母培养基(SC)和酵母提取物(YES)培养基的补充物,用于培养酵母细胞。

生化/生理作用

尿嘧啶及其衍生物在合成癌症、病毒感染、常染色体隐性遗传病、甲状腺和糖尿病药物的药物化学中不可或缺。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Sandra M Carvalho et al.
PloS one, 8(3), e58492-e58492 (2013-03-19)
Links between carbohydrate metabolism and virulence in Streptococcus pneumoniae have been recurrently established. To investigate these links further we developed a chemically defined medium (CDM) and standardized growth conditions that allowed for high growth yields of the related pneumococcal strains
William B White et al.
The New England journal of medicine, 369(14), 1327-1335 (2013-09-03)
To assess potentially elevated cardiovascular risk related to new antihyperglycemic drugs in patients with type 2 diabetes, regulatory agencies require a comprehensive evaluation of the cardiovascular safety profile of new antidiabetic therapies. We assessed cardiovascular outcomes with alogliptin, a new
Brian T Wilhelm et al.
Nature protocols, 5(2), 255-266 (2010-02-06)
Next-generation sequencing technologies are revolutionizing genomics research. It is now possible to generate gigabase pairs of DNA sequence within a week without time-consuming cloning or massive infrastructure. This technology has recently been applied to the development of 'RNA-seq' techniques for
Daisuke Katagiri et al.
Journal of the American Society of Nephrology : JASN, 24(12), 2034-2043 (2013-10-05)
Accumulating evidence of the beyond-glucose lowering effects of a gut-released hormone, glucagon-like peptide-1 (GLP-1), has been reported in the context of remote organ connections of the cardiovascular system. Specifically, GLP-1 appears to prevent apoptosis, and inhibition of dipeptidyl peptidase-4 (DPP-4)
Jaunius Urbonavicius et al.
Methods in enzymology, 425, 103-119 (2007-08-04)
Formation of 5-methyluridine (ribothymidine) at position 54 of the T-psi loop of tRNA is catalyzed by site-specific tRNA methyltransferases (tRNA[uracil-54,C5]-MTases). In eukaryotes and many bacteria, the methyl donor for this reaction is generally S-adenosyl-L-methionine (S-AdoMet). However, in other bacteria, like

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