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形狀
solid
品質等級
環保替代產品評分
old score: 2
new score: 1
Find out more about DOZN™ Scoring
環保替代產品特色
Less Hazardous Chemical Syntheses
Designing Safer Chemicals
Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
mp
>240 °C (dec.) (lit.)
環保替代類別
儲存溫度
room temp
SMILES 字串
NC(Cc1ccc(Cl)cc1)C(O)=O
InChI
1S/C9H10ClNO2/c10-7-3-1-6(2-4-7)5-8(11)9(12)13/h1-4,8H,5,11H2,(H,12,13)
InChI 密鑰
NIGWMJHCCYYCSF-UHFFFAOYSA-N
基因資訊
human ... TPH1(7166) , TPH2(121278)
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相关类别
一般說明
我们竭诚为您带来满足绿色替代产品四大类别要求的替代产品。本品属于重新设计产品类别,在“危险性较小的化学合成”、“设计更安全的化学品和产品”和“节能设计”绿色化学原则方面取得了重大改进。 点击此处查看其 DOZN 记分卡。
應用
4-氯-DL-苯丙氨酸用于:
- 作为色氨酸羟化酶1(TPH1)抑制剂,处理 kras+ 雄性斑马鱼
- 在大鼠模型中诱发失眠
- 处理胚胎,检查其对5-羟色胺的影响
- 选择带 pESentA32质粒的粪肠球菌( Enterococcus faecalis )转化体
- 饲喂苍蝇,研究5-羟色胺的作用
生化/生理作用
4-氯-DL-苯丙氨酸(PCPA)是5-羟色胺(5-HT)合成抑制剂。有助于改善肺部组织炎症和重塑肺动脉。PCPA 可减少色氨酸羟化酶1(TPH1)、基质金属蛋白酶(MMP)和促炎因子的表达。
色氨酸羟化酶抑制剂。
訊號詞
Danger
危險聲明
危險分類
Acute Tox. 3 Oral - Skin Sens. 1
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
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Chromatograms
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