所有图片(3)
About This Item
经验公式（希尔记法）:
C8H10BF4N3
CAS号:
分子量:
234.99
Beilstein:
5685616
MDL號碼:
分類程式碼代碼:
12352108
PubChem物質ID:
NACRES:
NA.32
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品質等級
形狀
powder
儲存溫度
−20°C
SMILES 字串
[F-].FB(F)F.CN(C)c1cc[n+](cc1)C#N
InChI
1S/C8H10N3.BF3.FH/c1-10(2)8-3-5-11(7-9)6-4-8;2-1(3)4;/h3-6H,1-2H3;;1H/q+1;;/p-1
InChI 密鑰
ONCRRSYBEJHQMM-UHFFFAOYSA-M
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一般說明
1-氰基-4-二甲氨基吡啶四氟硼酸酯是一种有机氰化剂，也称为CDAP。 基于其在酸性条件下的反应性，它是一种独特的胱氨酸标记试剂。这一特性使CDAP相较于其他巯基标记剂更具优势，因为它可避免可能的巯基-二巯基交换反应。
應用
1-氰基-4-二甲氨基吡啶四氟硼酸酯（CDAP）已作为一种氰化剂用于合成结合疫苗。用于免疫传感器的纤维素透析膜的激活使用CDAP作为激活剂。
特點和優勢
与类似试剂溴化氰（CNBr）相比，CDAP：
- 更易于使用。
- 可以在较低pH值下工作。
- 副作用更少。
- 溴化氰本身是一种有害物质。
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
从最新的版本中选择一种：
分析证书(COA)
Lot/Batch Number
其他客户在看
A Holmberg et al.
Bioconjugate chemistry, 4(6), 570-573 (1993-11-01)
This study presents a carrier system for boron, potentially useful in boron neutron capture therapy (BNCT). Na2B12H11SH (BSH) was covalently coupled to dextran derivatives. This was accomplished in two ways. The first method comprises activation of dextran with 1-cyano-4-(dimethylamino)pyridine (CDAP)
A Andersson et al.
International journal of cancer, 47(3), 439-444 (1991-02-01)
Some gliomas, melanomas and squamous carcinomas have large numbers of EGF receptors which could, in these cases, be used for targeting with toxic agents. We investigated whether EGF could be conjugated to dextran, which is a suitable carrier for toxic
Raphael Simon et al.
PloS one, 8(5), e64680-e64680 (2013-06-07)
Non-typhoidal Salmonella (NTS) serovars S. Enteritidis and S. Typhimurium are a major cause of invasive bacterial disease (e.g., bacteremia, meningitis) in infants and young children in sub-Saharan Africa and also occasionally cause invasive disease in highly susceptible hosts (young infants
J Wu et al.
Protein science : a publication of the Protein Society, 7(4), 1017-1028 (1998-05-06)
Human epidermal growth factor (hEGF) contains 53 amino acids and three disulfide bonds. The unfolded, reduced hEGF is allowed to refold under mildly alkaline conditions. The folding is quenched at different time points by adjusting the pH to 3.0 with
J T Watson et al.
Journal of molecular graphics & modelling, 19(1), 119-128 (2001-05-31)
Trapping folding intermediates of cystinyl proteins by covalent modification of free sulfhydryl groups provides the opportunity for isolation, purification, and structural elucidation of individual species. The disulfide structure of the intermediates, coupled with their temporal abundance, provides a 'snapshot' of
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