跳转至内容
Merck

B3188

Sigma-Aldrich

BYK204165

≥98% (HPLC)

别名:

4-(1-methyl-1H-pyrrol-2-ylmethylene)-4H-isoquinolin-1,3-dione

登录查看公司和协议定价


About This Item

经验公式(希尔记法):
C15H12N2O2
分子量:
252.27
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

品質等級

化驗

≥98% (HPLC)

形狀

powder

儲存條件

desiccated

顏色

yellow

溶解度

DMSO: >20 mg/mL

儲存溫度

2-8°C

SMILES 字串

Cn1cccc1\C=C2/C(=O)NC(=O)c3ccccc23

InChI

1S/C15H12N2O2/c1-17-8-4-5-10(17)9-13-11-6-2-3-7-12(11)14(18)16-15(13)19/h2-9H,1H3,(H,16,18,19)/b13-9-

InChI 密鑰

BTYSIDSTHDDAJW-LCYFTJDESA-N

基因資訊

human ... PARP1(142)
mouse ... PARP1(11545)
rat ... PARP1(25591)

生化/生理作用

BYK204165 is a potent and selective inhibitor of poly(ADP-ribose) polymerase 1 (PARP1). It is 100-fold selective for PARP-1 over PARP-2.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Skin Sens. 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Robin M Hallett et al.
Molecular oncology, 10(9), 1461-1472 (2016-09-08)
In the pediatric cancer neuroblastoma (NB), patients are stratified into low, intermediate or high-risk subsets based in part on MYCN amplification status. While MYCN amplification in general predicts unfavorable outcome, no clinical or genomic factors have been identified that predict
Facundo H Prado Spalm et al.
Molecular neurobiology, 56(7), 4760-4777 (2018-11-06)
Ceramide (Cer) has a key role inducing cell death and has been proposed as a messenger in photoreceptor cell death in the retina. Here, we explored the pathways induced by C2-acetylsphingosine (C2-Cer), a cell-permeable Cer, to elicit photoreceptor death. Treating
Erika A Newman et al.
Molecular cancer research : MCR, 13(3), 470-482 (2015-01-08)
In neuroblastoma, MYCN genomic amplification and segmental chromosomal alterations including 1p or 11q loss of heterozygocity and/or 17q gain are associated with progression and poor clinical outcome. Segmental alterations are the strongest predictor of relapse and result from unbalanced translocations

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门