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Merck

H1009

Sigma-Aldrich

过氧化氢 溶液

30 % (w/w) in H2O, contains stabilizer

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About This Item

经验公式(希尔记法):
H2O2
CAS号:
分子量:
34.01
Beilstein:
3587191
MDL號碼:
分類程式碼代碼:
12352304
PubChem物質ID:
NACRES:
NA.77

蒸汽壓力

23.3 mmHg ( 30 °C)

化驗

29.0-32.0% (titration)

形狀

liquid

儲存期限

~2 yr

反應適用性

reagent type: oxidant

濃度

30 % (w/w) in H2O

技術

cell based assay: suitable
immunohistochemistry: suitable

密度

1.110 g/cm3

適合性

suitable for DNA precipitation

應用

general analytical
pharmaceutical

儲存溫度

2-8°C

SMILES 字串

OO

InChI

1S/H2O2/c1-2/h1-2H

InChI 密鑰

MHAJPDPJQMAIIY-UHFFFAOYSA-N

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一般說明

过氧化氢(H2O2)是一种局部杀菌剂,在需氧细胞中作为有氧呼吸的副产物合成。它还可作为过氧化物酶体、线粒体或其他细胞区室中酶促反应的产物。

應用

过氧化氢溶液已用于:
  • 处理鼻上皮细胞,用于H2O2敏感性测定
  • 处理人永生化角质形成细胞系(HaCaT)和人黑色素瘤细胞系(GLL19)以诱导衰老
  • 孵育脑切片,进行溴脱氧尿苷 (BrdU)/NeuN染色
  • 细胞增殖测定,孵育体外实验所用的神经干细胞(NE-4C)

生化/生理作用

过氧化氢(H2O2)主要用于创口清洁。它可以通过氧化爆发和产生局部氧气来杀死病原体。H2O2可充当信号传导分子或第二信使。它以多种方式在基因表达中发挥关键作用。H2O2参与炎症调节。

特點和優勢

《受体分类和信号转导》手册的 磷蛋白磷酸酶(酪氨酸) 页面有该化合物的介绍。想要浏览手册的其他页面, 请单击此处

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象形圖

Corrosion

訊號詞

Danger

危險聲明

危險分類

Aquatic Chronic 3 - Eye Dam. 1

儲存類別代碼

5.1B - Oxidizing hazardous materials

水污染物質分類(WGK)

WGK 1

個人防護裝備

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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S V Lennon et al.
Cell proliferation, 24(2), 203-214 (1991-03-01)
Cell death may occur by either of two mechanisms: apoptosis or necrosis. Necrosis, the first type of cell death to be recognized, is an uncontrolled degenerative phenomenon invariably caused by noxious stimuli and is the result of irreversible failure of
Akitoshi Nakashima et al.
Scientific reports, 9(1), 11466-11466 (2019-08-09)
Pregnancy is a stress factor culminating into mild endoplasmic reticulum (ER) stress, which is necessary for placental development. However, excessive or chronic ER stress in pre-eclamptic placentas leads to placental dysfunction. The precise mechanisms through which excessive ER stress impacts
Stephen J D O'Keefe et al.
Nature communications, 6, 6342-6342 (2015-04-29)
Rates of colon cancer are much higher in African Americans (65:100,000) than in rural South Africans (<5:100,000). The higher rates are associated with higher animal protein and fat, and lower fibre consumption, higher colonic secondary bile acids, lower colonic short-chain
Shoichi Iriguchi et al.
Blood, 125(2), 370-382 (2014-10-29)
Although overexpression of T-bet, a master transcription factor in type-1 helper T lymphocytes, has been reported in several hematologic and immune diseases, its role in their pathogenesis is not fully understood. In the present study, we used transgenic model mice
Osamu Sakai et al.
Investigative ophthalmology & visual science, 56(1), 538-543 (2015-01-13)
The purpose of the present study was to investigate the role of glutathione peroxidase 4 (GPx4) in conjunctival epithelial cells. An immortalized human conjunctival epithelial cell line was used. Cells were transfected with catalase, GPx1, GPx4, SOD1, SOD2, or control

商品

This solution is used as a substrate for detecting horseradish-peroxidase conjugates in Western blotting.

实验方案

This procedure may be used for all Catalase products.

This procedure is for the determination of Peroxidase enzymatic activity using Pyrogallol as the substrate.

This procedure is for the determination of Peroxidase enzymatic activity using Pyrogallol as the substrate.

To standardize a procedure for the assay of Peroxidase using 2,2'-Azino-bis(3-Ethylbenzthiazoline-6-Sulfonic Acid) as a substrate.

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