所有图片(1)
About This Item
经验公式（希尔记法）:
C12H22N6O6
CAS号:
分子量:
346.34
MDL號碼:
分類程式碼代碼:
12352209
PubChem物質ID:
NACRES:
NA.32
推荐产品
生物源
synthetic
品質等級
化驗
≥97% (TLC)
形狀
powder
技術
cell culture | stem cell: suitable
UniProt登錄號
儲存溫度
−20°C
SMILES 字串
N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(O)=O
InChI
1S/C12H22N6O6/c13-6(2-1-3-16-12(14)15)10(22)17-5-8(19)18-7(11(23)24)4-9(20)21/h6-7H,1-5,13H2,(H,17,22)(H,18,19)(H,20,21)(H,23,24)(H4,14,15,16)/t6-,7-/m0/s1
InChI 密鑰
IYMAXBFPHPZYIK-BQBZGAKWSA-N
基因資訊
human ... FN1(2335)
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Amino Acid Sequence
Arg-Gly-Asp
一般說明
Arg-Gly-Asp（RGD）是整合素结合位点，属于粘附蛋白类。它可作为脑肿瘤靶向配体。
應用
Arg-Gly-Asp用于：
- 使细胞表面Arg-Gly-Asp（RGD）受体饱和，抑制骨髓基质细胞（MSC）与肽修饰水凝胶的粘附
- 粘附检测
- 抑制实验，以证实细胞粘附的β1-整合素依赖性
- 纺织品制造和RGD纺织品功能化
- 构建迁移受损的人真皮成纤维细胞群
- 修饰玻璃衬底并评估人骨髓间充质干细胞（hBM-MSC）的行为
- 人乳腺上皮细胞的细胞培养
生化／生理作用
一级序列涉及蛋白与细胞表面的结合
包裝
无底玻璃瓶。内容物在嵌入的融合锥中。
準備報告
来自纤连蛋白的细胞粘附结构域的三肽
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
Leo J Hofland et al.
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Biology of Reproduction, 60(6), 1468-1474 (1999)
Cell attachment to thrombospondin: the role of ARG-GLY-ASP, calcium, and integrin receptors.
Lawler J, et al.
The Journal of cell biology, 107(6), 2351-2361 (1988)
Bio-active molecules modified surfaces enhanced mesenchymal stem cell adhesion and proliferation
Mobasseri R, et al.
Biochemical and biophysical research communications, 483(1), 312-317 (2017)
J Takagi
Biochemical Society transactions, 32(Pt3), 403-406 (2004-05-26)
Since the discovery of the RGD sequence motif as the essential cell attachment site in Fn (fibronectin), RGD-dependent ligand recognition by integrins has been the major focus of many integrin researches. Although many integrins recognize RGD-containing ligands, it is believed
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