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Merck
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Key Documents

SCP0147

Sigma-Aldrich

FR-1, cyclic

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About This Item

经验公式(希尔记法):
C35H57N13O16S2
分子量:
980.03
分類程式碼代碼:
12352202
NACRES:
NA.32

化驗

≥95% (HPLC)

形狀

lyophilized

成份

Peptide Content, ≥78%

儲存條件

protect from light

儲存溫度

−20°C

Amino Acid Sequence

Cys-Arg-Gly-Asp-Ser-Pro-Ala-Ser-Ser-Cys

應用

FR-1 is a cyclic RGDS peptide that acts via binding to FR-1 receptor, a 57 kDa Arg-Gly-Asp-Ser (RGDS)-binding protein involved in early embryogenesis.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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H Katow et al.
Development, growth & differentiation, 39(2), 207-219 (1997-04-01)
A fibronectin-related synthetic cyclic H-Cys-Arg-Gly-Asp-Ser-Pro-Ala-Ser-Ser-Cys-OH (RGDSPASS) peptide (FR-1) binding site in the embryo of the sand dollar Clypeaster japonicus was specified using dansyl-labeled FR-1 (Dns-FR-1) and horseradish peroxidase-labeled FR-1, and an FR-1 receptor was isolated using FR-1-affinity column chromatography. The
H Katow et al.
Development, growth & differentiation, 43(5), 601-610 (2001-09-29)
Immunoblotting using polyclonal antibodies (pAb) raised against an FR-1 receptor (FR-1R), a 57 kDa Arg-Gly-Asp-Ser (RGDS)-binding protein, of the sand dollar Clypeaster japonicus showed that the pAb monospecifically bound to the protein. FR-1R was present in purified plasma membrane, suggesting

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