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Merck

10127647001

Roche

D-葡萄糖-6-磷酸 二钠盐 水合物

mol wt (glucose-6-P: Mr = 260.2, glucose-6-P-Na2: Mr = 304.2), pkg of 5 g

别名:

G-6-P-Na2, 鲁氏酯

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About This Item

经验公式(希尔记法):
C6H11Na2O9P · xH2O
CAS号:
分子量:
304.10 (anhydrous basis)
Beilstein:
5199009
MDL號碼:
分類程式碼代碼:
12352302
PubChem物質ID:

形狀

solid

分子量

(glucose-6-P: Mr = 260.2, glucose-6-P-Na2: Mr = 304.2)

包裝

pkg of 5 g

製造商/商標名

Roche

運輸包裝

ambient

SMILES 字串

O.[Na+].[Na+].OC1O[C@H](COP([O-])([O-])=O)[C@@H](O)[C@H](O)[C@H]1O

InChI

1S/C6H13O9P.2Na.H2O/c7-3-2(1-14-16(11,12)13)15-6(10)5(9)4(3)8;;;/h2-10H,1H2,(H2,11,12,13);;;1H2/q;2*+1;/p-2/t2-,3-,4+,5-,6?;;;/m1.../s1

InChI 密鑰

UUWJZXLTPORJKW-WYFATIGWSA-L

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一般說明

Disodium salt

應用

Substrate for glucose-6-phosphatase.

生化/生理作用

In mammals, glucose-6-phosphate (G6P) is formed by a kinase acting on glucose. It plays several roles and has its fate determined accordingly. It can get converted back to glucose by a phosphatase enzyme. It can pass into glycogen, or enter into the energy-yielding Embden-Meyerhof path or into the 6-phosphogluconate pathway. Increased levels of blood glucose result in elevated levels of glucose 6-phosphate in liver, skeletal muscle, and adipose tissue. This elevated intracellular level of G6P activates glycogen synthase. G6P may also be involved in the negative regulation of phosphorylation of glycogen synthase via cyclic AMP-stimulated protein kinase.

成分

77% glucose-6-P (enzymatic), 13% sodium, 8% water

品質

Contaminants: <0.2% glucose (enzymatic)

公式變體

C6H11O9PNa2

其他說明

仅用于生命科学研究。不可用于诊断。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

does not flash

閃點(°C)

does not flash


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C Villar-Palasí et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 11(7), 544-558 (1997-06-01)
Elevated blood glucose concentrations result in increased intracellular levels of glucose 6-phosphate in liver, skeletal muscle, and adipose tissue. In liver, blood glucose concentrations are the main factor in control of the synthesis of glycogen; insulin has only a potentiating
THE ROLE OF GLUCOSE 6-PHOSPHATE IN THE REGULATION OF GLUCOSE METABOLISM IN HUMAN ERYTHROCYTES.
I A ROSE et al.
The Journal of biological chemistry, 239, 12-17 (1964-01-01)

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