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形狀
solid
分子量
(glucose-6-P: Mr = 260.2, glucose-6-P-Na2: Mr = 304.2)
包裝
pkg of 5 g
製造商/商標名
Roche
運輸包裝
ambient
SMILES 字串
O.[Na+].[Na+].OC1O[C@H](COP([O-])([O-])=O)[C@@H](O)[C@H](O)[C@H]1O
InChI
1S/C6H13O9P.2Na.H2O/c7-3-2(1-14-16(11,12)13)15-6(10)5(9)4(3)8;;;/h2-10H,1H2,(H2,11,12,13);;;1H2/q;2*+1;/p-2/t2-,3-,4+,5-,6?;;;/m1.../s1
InChI 密鑰
UUWJZXLTPORJKW-WYFATIGWSA-L
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一般說明
Disodium salt
應用
Substrate for glucose-6-phosphatase.
生化/生理作用
In mammals, glucose-6-phosphate (G6P) is formed by a kinase acting on glucose. It plays several roles and has its fate determined accordingly. It can get converted back to glucose by a phosphatase enzyme. It can pass into glycogen, or enter into the energy-yielding Embden-Meyerhof path or into the 6-phosphogluconate pathway. Increased levels of blood glucose result in elevated levels of glucose 6-phosphate in liver, skeletal muscle, and adipose tissue. This elevated intracellular level of G6P activates glycogen synthase. G6P may also be involved in the negative regulation of phosphorylation of glycogen synthase via cyclic AMP-stimulated protein kinase.
成分
77% glucose-6-P (enzymatic), 13% sodium, 8% water
品質
Contaminants: <0.2% glucose (enzymatic)
公式變體
C6H11O9PNa2
其他說明
仅用于生命科学研究。不可用于诊断。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 1
閃點(°F)
does not flash
閃點(°C)
does not flash
其他客户在看
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 11(7), 544-558 (1997-06-01)
Elevated blood glucose concentrations result in increased intracellular levels of glucose 6-phosphate in liver, skeletal muscle, and adipose tissue. In liver, blood glucose concentrations are the main factor in control of the synthesis of glycogen; insulin has only a potentiating
THE ROLE OF GLUCOSE 6-PHOSPHATE IN THE REGULATION OF GLUCOSE METABOLISM IN HUMAN ERYTHROCYTES.
The Journal of biological chemistry, 239, 12-17 (1964-01-01)
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