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Merck
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Key Documents

MAB3306

Sigma-Aldrich

Anti-MMP-3 Antibody, cross reacts w/hMMP-10, clone 55-2A4

clone 55-2A4, Chemicon®, from mouse

别名:

Stromelysin-1, Transin, Proteoglycanase

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

55-2A4, monoclonal

物種活性

human, pig, rat, sheep

應無反應活性

bovine, rabbit, mouse

製造商/商標名

Chemicon®

技術

ELISA: suitable
immunohistochemistry: suitable (paraffin)
western blot: suitable

同型

IgG1κ

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

human ... MMP3(4314)

特異性

The antibody specifically reacts with precursor and active forms of human MMP-3. This is a purified mouse monoclonal antibody to human matrix metalloproteinase 3 (human MMP-3, stromelysin-1) from synovial cells. The antibody cross reacts 34% with human MMP-10.

免疫原

Epitope: cross reacts w/hMMP-10
Human matrix metalloproteinase 3 (human MMP-3, stromelysin-1) from synovial cells.

應用

Immunoblotting (0.5 μg/mL)

Immunohistochemistry on paraffin-embedded tissues (5-10μg/mL, PLP fixation required, not recommended for traditional formalin fixation. Immunohistochemistry on fresh frozen sections (0.5 μg/mL)

ElA
Research Category
Cell Structure
Research Sub Category
MMPs & TIMPs
This Anti-MMP-3 Antibody, cross reacts w/hMMP-10, clone 55-2A4 is validated for use in ELISA, WB, IH(P) for the detection of MMP-3.

外觀

Format: Purified
Liquid in 0.01M Na-Phosphate buffer, pH 7.0, 125 mM NaCl, containing 2% protease free bovine serum albumin.

儲存和穩定性

Maintain frozen at -20°C in undiluted aliquots for up to 12 months.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Manufactured by Daiichi Fine Chemical Co., Ltd

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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K Obata et al.
Clinica chimica acta; international journal of clinical chemistry, 211(1-2), 59-72 (1992-10-15)
A one-step sandwich enzyme immunoassay (EIA) for matrix metalloproteinase 3 (MMP-3; stromelysin-1) was developed. The assay system used two simultaneous immunoreactions using a solid phase monoclonal antibody and a horseradish peroxidase-labeled monoclonal antibody (Fab'). The sensitivity of the assay system
Christelle Sanchez et al.
Arthritis and rheumatism, 64(4), 1193-1203 (2011-10-29)
Recent data have shown that abnormal subchondral bone remodeling plays an important role in osteoarthritis (OA) onset and progression, and it was suggested that abnormal mechanical pressure applied to the articulation was responsible for these metabolic changes. This study was
Genomic and proteomic profiling of oxidative stress response in human diploid fibroblasts.
Lifang Xie, Ritu Pandey, Beibei Xu, George Tsaprailis, Qin M Chen, Lifang Xie et al.
Biogerontology null
Iraklis Papageorgiou et al.
Nanomaterials (Basel, Switzerland), 4(2), 485-504 (2014-06-16)
Medical interventions for the treatment of spinal disc degeneration include total disc replacement and fusion devices. There are, however, concerns regarding the generation of wear particles by these devices, the majority of which are in the nanometre sized range with
Journal of dental research
Ogbureke, KU; Fisher, LW
Journal of Dental Research null

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