236603
C-Reactive Protein, Human Serum, High Purity
C-Reactive Protein, Human Serum, High Purity, CAS 9007-41-4, is a major acute-phase plasma protein. Useful as a calibration standard for assays of CRP and as an antigen for production of antisera.
别名:
C-Reactive Protein, Human Serum, High Purity, CRP
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About This Item
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品質等級
化驗
≥99% (SDS-PAGE)
形狀
liquid
製造商／商標名
Calbiochem®
儲存條件
OK to freeze
avoid repeated freeze/thaw cycles
運輸包裝
wet ice
儲存溫度
−70°C
一般說明
M.W. 23,000 (monomer); 115,000 (pentamer).
Native C-reactive protein highly purified from human serum. CRP is a major acute-phase plasma protein that is dramatically elevated in patients with acute-phase conditions. Composed of five identical noncovalently linked subunits. Exhibits Ca2+-dependent binding to a variety of substrates. Important in diagnosis of rheumatoid arthritis. Suitable for immunological studies. In purified states and in plasma the monomeric form (M.W. ~21 kDa) aggregates as a cyclic pentamer. Intended for use as a calibration standard for assays of CRP, for structural and functional studies, and as an antigen for production of antisera.Calibrated by electroimmunoassay against WHO reference standard or equivalent.
No reaction in ODD and Laurell electroimmunoassay against polyvalent antiserum to normal human serum, antiserum to pooled effusion fluids and monospecific antiserum to human IgG.
警告
Toxicity: Standard Handling (A)
外觀
In 140 mM NaCl, 10 mM Tris, 2 mM CaCl₂, 0.1% NaN₃, pH 8.0.
準備報告
Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
重構
Following initial thaw, aliquot and freeze (-70°C).
其他說明
Paffen, E., et al. 2004. Arterioscler. Thromb. Vasc. Biol.24, 975.
法律資訊
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
其他客户在看
Elaine Paffen et al.
Arteriosclerosis, thrombosis, and vascular biology, 24(5), 975-981 (2004-03-27)
It is generally assumed that C-reactive protein (CRP) induces synthesis of tissue factor (TF) in monocytic cells, thereby potentially initiating intravascular blood coagulation. We aimed to elucidate the mechanism of CRP-induced TF expression in monocytes and monocyte-derived macrophages (MDMs) in
Dobrin Nedelkov
Analytical chemistry, 79(15), 5987-5990 (2007-06-26)
Protein microarrays are the format of choice for high-throughput, high-content protein interaction analysis. In most of the array formats, reporter molecules are used in multistep detection of the protein interactions. Among the few existing label-free detection approaches, surface plasmon resonance
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