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Merck
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主要文件

236600

Sigma-Aldrich

C-Reactive Protein, Human Ascites

C - reactive protein, Human Ascites, CAS 9007-41-4, is a major acute-phase plasma protein that composed of five identical non-covalently linked subunits.

别名:

C-Reactive Protein, Human Ascites, CRP

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About This Item

CAS号:
MDL號碼:
分類程式碼代碼:
12352202
NACRES:
NA.25

品質等級

描述

Merck USA index - 14, 2603

形狀

liquid

製造商/商標名

Calbiochem®

儲存條件

OK to freeze

溶解度

water: soluble

運輸包裝

wet ice

儲存溫度

2-8°C

一般說明

M.W. 23,000 (monomer); 115,000 (pentamer).
Native C-reactive protein from human ascites. CRP is a major acute-phase plasma protein that is dramatically elevated in patients with acute-phase conditions. Composed of five identical noncovalently linked subunits. Exhibits Ca2+-dependent binding to a variety of substrates. Important in diagnosis of rheumatoid arthritis. Suitable for immunological studies. In purified states and in plasma the monomeric form (M.W. ~21 kDa) aggregates as a cyclic pentamer.

包裝

Please refer to vial label for lot-specific concentration.

警告

Toxicity: Standard Handling (A)

外觀

In 150 mM NaCl, 20 mM Tris, 2 mM CaCl₂, 0.1% NaN₃, pH 7.5.

準備報告

Prepared from ascites that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

分析報告

Single band by SDS-PAGE

其他說明

Christner, R.B., and Mortensen, R.F. 1994. J. Biol. Chem. 269, 9760.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Katrine Pilely et al.
Frontiers in immunology, 8, 1040-1040 (2017-09-14)
Inflammation is a part of the initial process leading to atherosclerosis and cholesterol crystals (CC), found in atherosclerotic plaques, which are known to induce complement activation. The pentraxins C-reactive protein (CRP), long pentraxin 3 (PTX3), and serum amyloid P component

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