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生物源
human
品質等級
100
300
重組細胞
expressed in baculovirus infected Sf21 cells
分子量
Mw 63.2 kDa
製造商／商標名
Upstate®
技術
activity assay: suitable (kinase)
NCBI登錄號
UniProt登錄號
基因資訊
human ... PAK3(5063)
一般說明
C-terminal 6His-tagged, recombinant, human full length, PAK3.
mitosis
mitosis
Product Source: PAK3 expressed by baculovirus in Sf21 cells.
應用
Research Category
Inflammation & Immunology
Inflammation & Immunology
生化／生理作用
Protein Target: PAK3
Target Sub-Family: STE
品質
routinely evaluated by phosphorylation of PAKtide (RRRLSFAEPG).
外觀
Ni2+/NTA-agarose
儲存和穩定性
6 months at -70°C from date of shipment
其他說明
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
法律資訊
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
訊號詞
Warning
危險聲明
危險分類
Skin Sens. 1
儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
J Roig et al.
Vitamins and hormones, 62, 167-198 (2001-05-11)
The p21-activated protein kinase gamma-PAK, also known as PAK2, has very different properties from the other two highly conserved isoforms of the PAK family, alpha-PAK (PAK1) and beta-PAK (PAK3). gamma-PAK has cytostatic activity, as shown by inhibition of cleavage of
Ger J A Ramakers
Trends in neurosciences, 25(4), 191-199 (2002-05-10)
For several decades, it has been known that mental retardation (MR) is associated with abnormalities in dendrites and dendritic spines. The recent cloning of seven genes that cause nonspecific MR when mutated provides important insights in the cellular mechanisms that
Rho proteins, mental retardation and the neurobiological basis of intelligence.
van Galen, Elly J M and Ramakers, Ger J A
Progress in Brain Research, 147, 295-317 (2005)
Zahara M Jaffer et al.
The international journal of biochemistry & cell biology, 34(7), 713-717 (2002-04-16)
The p21-activated kinases (Paks) are serine/threonine protein kinases that bind to and, in some cases, are stimulated by activated forms of the small GTPases, Cdc42 and Rac. With the recent discovery of several novel isoforms, Paks are now categorized into
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