1.11474

1,4-二硫苏糖醇

for biochemistry

• 别名: 1,4-二硫苏糖醇, DTT，Cleland’s试剂
• 线性分子式: (C₂H₃OHSH)₂
• CAS号: 3483-12-3
• 分子量: 154.25
• MDL號碼: MFCD00004877
• 分類程式碼代碼: 12352104
• 酶委員會索引編號: 222-468-7
• NACRES: NB.21

属性

• 等級: for biochemistry
• 品質等級: 200
• 化驗: ≥99% (iodometric)
• 形狀: solid
• 效力: 400 mg/kg LD₅₀, oral (Rat)
• 反應適用性: reagent type: reductant
• pH值: 5.1 (20 °C, 10 g/L in H₂O)
• mp: 40-43 °C
• 轉變溫度: flash point >110 °C
• 體積密度: 300 kg/m³
• 儲存溫度: 2-8°C
• InChI: 1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4-/m0/s1
• InChI 密鑰: VHJLVAABSRFDPM-IMJSIDKUSA-N

说明

應用

• Drug delivery using reduction-responsive hydrogel based on carboxyethyl-succinoglycan with highly improved rheological, antibacterial, and antioxidant properties.: This study explores the application of 1,4-Dithiothreitol in developing reduction-responsive hydrogels, highlighting significant enhancements in rheological, antibacterial, and antioxidant characteristics, suitable for drug delivery systems (Kim et al., 2024).


• Preparation and properties of hydrogel photonic crystals assembled by biodegradable nanogels.: Research discusses the integration of 1,4-Dithiothreitol in the assembly of hydrogel photonic crystals using biodegradable nanogels, emphasizing their potential in creating novel photonic materials (Zhang et al., 2024).


• Optimized total RNA isolation from bovine sperm with enhanced sperm head lysis.: The paper highlights the use of 1,4-Dithiothreitol in optimizing RNA isolation techniques from bovine sperm, which enhances sperm head lysis, crucial for reproductive biology studies (Tiwari et al., 2024).


• Preparation of a Convertible Spacer Containing a Disulfide Group for Versatile Functionalization of Oligonucleotides.: Discusses the synthesis of a convertible spacer containing a disulfide group using 1,4-Dithiothreitol, enabling versatile functionalization of oligonucleotides for therapeutic and diagnostic applications (Pontarelli et al., 2023).

分析報告

含量测定（碘量滴定法）： ≥ 99 %
鉴别（红外光谱）：通过测试
熔点：40 - 43 °C
重金属（以Pb计）： ≤ 10 ppm
Fe（铁）： ≤ 5 ppm

安全信息

• 象形圖: GHS05,GHS07
• 訊號詞: Danger
• 危險聲明: H302 - H315 - H318
• 防範說明: P264 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P332 + P313
• 危險分類: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable