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生物源
mouse
品質等級
抗體表格
purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
16C2, monoclonal
物種活性
mouse, rat, human
製造商／商標名
Upstate®
技術
flow cytometry: suitable
immunocytochemistry: suitable
western blot: suitable
同型
IgG1κ
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
phosphorylation (pSer239)
基因資訊
human ... VASP(7408)
特異性
基于序列同源性，预计该抗体也会与犬和牛发生交叉反应。
磷酸化VASP
免疫原
磷酸化肽，对应于人磷酸化VASP（RKV[pS]KQE）的236-242位氨基酸
應用
研究子类别
细胞骨架信号转导
细胞骨架信号转导
研究类别
信号传导
信号传导
该抗磷酸化VASP (Ser239)抗体，克隆16C2经过验证可用在FC、WB、IC中，检测磷酸化VASP (Ser239)。
品質
通过免疫印迹对CTLL细胞的RIPA裂解液进行了常规评估
標靶描述
50kDa
外觀
100 µg来自无血清细胞培养上清液的小鼠IgG1，通过亲硫吸附和尺寸排阻色谱法纯化。 从1 ml PBS、0.1%叠氮化钠、PEG和蔗糖中冻干。 冻干粉末。用100 µL H2O复溶（15 min，RT），使最终浓度为1 mg/mL。 储存于 -20°C。
亲硫吸附色谱
形式：纯化
儲存和穩定性
在-20°C下可保存2年
法律資訊
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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儲存類別代碼
10 - Combustible liquids
Insulin stimulates glucose transport via nitric oxide/cyclic GMP pathway in human vascular smooth muscle cells.
Bergandi, L; Silvagno, F; Russo, I; Riganti, C; Anfossi, G; Aldieri, E; Ghigo, D; Trovati et al.
Arteriosclerosis, Thrombosis, and Vascular Biology null
I Kishimoto et al.
Journal of neuroendocrinology, 20(11), 1213-1223 (2008-08-30)
Cyclic GMP (cGMP) is known to play important roles for neuronal development and neurite pathfinding. However, the regulatory mechanism that governs the synthesis of cGMP in the nervous system is not well defined. In the present study, we examined the
A Mülsch et al.
Circulation, 103(17), 2188-2194 (2001-05-23)
Chronic in vivo treatment with nitroglycerin (NTG) induces tolerance to nitrates and cross-tolerance to nitrovasodilators and endothelium-derived nitric oxide (NO). We previously identified increased vascular superoxide formation and reduced NO bioavailability as one causal mechanism. It is still controversial whether
Eberhard Schulz et al.
Circulation, 105(10), 1170-1175 (2002-03-13)
In experimental animal models, long-term in vivo treatment with nitroglycerin (NTG) induces both endothelial dysfunction and tolerance to nitrates. However, it is still controversial whether nitrate tolerance in humans is associated with both endothelial dysfunction and impaired vascular response to
Jonel Trebicka et al.
Hepatology (Baltimore, Md.), 47(4), 1264-1276 (2008-03-06)
In cirrhosis, splanchnic vasodilation contributes to portal hypertension, subsequent renal sodium retention, and formation of ascites. Urotensin II(U-II) is a constrictor of large conductive vessels. Conversely, it relaxes mesenteric vessels, decreases glomerular filtration, and increases renal sodium retention. In patients
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
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