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VASP

vasodilator-stimulated phosphoprotein

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(7408) Summary: Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. [provided by RefSeq, Jul 2008]
  • Mouse(22323) vasodilator-stimulated phosphoprotein
  • Rat(361517) vasodilator-stimulated phosphoprotein
  • Zebrafish(550487) vasodilator-stimulated phosphoprotein
  • dog(403936) vasodilator-stimulated phosphoprotein
  • domestic cat(101094805) vasodilator-stimulated phosphoprotein
  • domestic guinea pig(100722137) vasodilator-stimulated phosphoprotein
  • naked mole-rat(101708295) vasodilator-stimulated phosphoprotein
  • cow(514902) vasodilator-stimulated phosphoprotein
  • sheep(101113616) vasodilator-stimulated phosphoprotein

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-phospho-VASP (pSer239) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-VASP (Ab-157) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
immunofluorescence
western blot
Anti-Phospho-VASP-S239 antibody produced in rabbit, ,
Species Reactivity
human
Application
immunohistochemistry
western blot
PhosphoDetect Anti-VASP (pSer¹⁵⁷) Mouse mAb (5C6), lyophilized, clone 5C6, Calbiochem®,
Species Reactivity
human, mouse
Application
Anti-Phospho-VASP-S157 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human VASP,
Species
human
MISSION® esiRNA, targeting mouse Vasp,
Species
mouse