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Merck

B3253

Sigma-Aldrich

碘化丁酰硫代胆碱

≥98%

别名:

(2-巯乙基)三甲基碘化铵丁酸酯

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About This Item

线性分子式:
(CH3)3N(I)CH2CH2SCOCH2CH2CH3
CAS号:
分子量:
317.23
Beilstein:
3729509
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

≥98%

形狀

powder

mp

171-174 °C (lit.)

儲存溫度

−20°C

SMILES 字串

[I-].CCCC(=O)SCC[N+](C)(C)C

InChI

1S/C9H20NOS.HI/c1-5-6-9(11)12-8-7-10(2,3)4;/h5-8H2,1-4H3;1H/q+1;/p-1

InChI 密鑰

WEQAAFZDJROSBF-UHFFFAOYSA-M

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一般說明

碘化丁酰硫胆碱是丁酰胆碱的一种含硫类似物,用作丁酰胆碱酯酶活性测定试剂。

應用

  • 丁酰胆碱酯酶的无标记、超灵敏检测:研究采用基于Mn(II)的电子自旋共振波谱法,超灵敏检测丁酰胆碱酯酶。在有机磷农药存在下,以碘化丁酰硫代胆碱为底物测定酶活性。代表生化试验应用。(Tang et al., 2022)。
  • 用于生物传感的新型纳米酶:研发开发了一种Co, N共掺的多孔碳基纳米酶,可作为类氧化酶用于丁酰胆碱酯酶的荧光和比色法生物传感检测。其中,碘化丁酰硫代胆碱为关键底物。代表酶动力学分析相关应用(Sun et al., 2022)。
  • 抗阿兹海默症′药物筛选的检测系统:研究构建了铜纳米簇和MnO2纳米片荧光检测平台,用于检测丁酰胆碱酯酶活性(利用碘化丁酰硫代胆碱),继而可用于筛选抗阿兹海默病′药物,并检测胆碱能系统相互作用(Chen et al., 2022)。
  • 丁酰胆碱酯酶的双通道检测:研究介绍了融合荧光和氧化酶活性的双功能金属有机框架,开发用于双通道检测丁酰胆碱酯酶(使用碘化丁酰硫代胆碱),改进生化试验方法。(Wang et al., 2022)。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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