900600

3-(Fluorosulfonyl)-5-((trimethylsilyl)ethynyl)benzoic acid

≥95%

• 别名: Carboxyl sulfonyl fluoride alkyne, Probe building block
• 经验公式（希尔记法）: C₁₂H₁₃FO₄SSi
• CAS号: 2088829-06-3
• 分子量: 300.38
• MDL號碼: MFCD30737995
• 分類程式碼代碼: 12352106
• NACRES: NA.22

属性

• 化驗: ≥95%
• 形狀: solid
• 反應適用性: reagent type: cross-linking reagent
• 存貨情形: available only in USA
• 儲存溫度: −20°C
• SMILES 字串: O=S(C1=CC(C#C[Si](C)(C)C)=CC(C(O)=O)=C1)(F)=O

说明

應用

3-(Fluorosulfonyl)-5-((trimethylsilyl)ethynyl)benzoic acid is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and carboxylic acid synthetic handle. When appended to a ligand or pharmacophore through its acid linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

其他說明

Technology Spotlight: Trifuctional Probe Building Blocks

Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis

安全信息

• 象形圖: GHS02,GHS07
• 訊號詞: Danger
• 危險聲明: H242,H315,H319
• 防範說明: P210 - P235 - P302 + P352 - P305 + P351 + P338 - P370 + P378 - P403
• 危險分類: Eye Irrit. 2 - Self-react. C - Skin Irrit. 2
• 儲存類別代碼: 5.2 - Organic peroxides and self-reacting hazardous materials
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable