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760676

Sigma-Aldrich

二苄环辛基-PEG4-马来酰亚胺

for Copper-free Click Chemistry

别名:

DBCO-PEG4-马来酰亚胺

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About This Item

经验公式（希尔记法）:
C36H42N4O9
分子量:
674.74
MDL號碼:
MFCD22572659
分類程式碼代碼:
12161502
PubChem物質ID:
329766888
NACRES:
NA.22

形狀

solid

反應適用性

reaction type: click chemistry
reagent type: cross-linking reagent

官能基

maleimide

儲存溫度

−20°C

SMILES 字串

O=C(CCNC(CCOCCOCCOCCOCCNC(CCN1C(C=CC1=O)=O)=O)=O)N2CC3=C(C=CC=C3)C#CC4=C2C=CC=C4

InChI

1S/C36H42N4O9/c41-32(14-18-39-34(43)11-12-35(39)44)38-17-20-47-22-24-49-26-25-48-23-21-46-19-15-33(42)37-16-13-36(45)40-27-30-7-2-1-5-28(30)9-10-29-6-3-4-8-31(29)40/h1-8,11-12H,13-27H2,(H,37,42)(H,38,41)

InChI 密鑰

VVFZXPZWVJMYPX-UHFFFAOYSA-N

相关类别

應用

马来酰亚胺功能化环辛炔衍生物，用于将环辛炔基团掺入含巯基化合物或生物分子。环辛烯在促进无铜叠氮炔环加成反应中是有用的。这种二苯并环辛炔将与叠氮官能化化合物或生物分子反应，而不需要 Cu (I) 催化剂产生稳定的三唑键。PEG 亲脂性间隔物有助于减少标记生物分子时的聚集和沉淀问题。
应用包括：
  • 蛋白-肽结合物
  • 抗体酶或抗体-药物偶联物
  • 蛋白或肽-寡核苷酸结合物
  • 表面改性

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
MKCN2592
MKCQ3414
MKCQ0196
MKCP2052
MKCM7716

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Copper-Free Click Chemistry

Copper-free click chemistry is an alternative approach to click chemistry that proceeds at a lower activation barrier and is free of cytotoxic transition metal catalysts.

Copper-Free Click Chemistry

Copper-free click chemistry is an alternative approach to click chemistry that proceeds at a lower activation barrier and is free of cytotoxic transition metal catalysts.

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