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479675

N-(叔丁基)羟胺乙酸酯

Name: <I>N</I>-(叔丁基)羟胺乙酸酯
Brand: ALDRICH

97%

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About This Item

线性分子式:

(CH₃)₃CNHOH·CH₃CO₂H

CAS号:

253605-31-1

分子量:

149.19

MDL號碼:

MFCD01321354

分類程式碼代碼:

12352100

PubChem物質ID:

24871640

NACRES:

NA.22

化驗

97%

mp

65-69 °C (lit.)

SMILES 字串

CC(O)=O.CC(C)(C)NO

InChI

1S/C4H11NO.C2H4O2/c1-4(2,3)5-6;1-2(3)4/h5-6H,1-3H3;1H3,(H,3,4)

InChI 密鑰

QGYZLVSWEOXOFT-UHFFFAOYSA-N

一般說明

N-(tert-Butyl)hydroxylamine acetate (NtBuHA acetate) is a derivative of hydroxylamine that shows thioesterase-mimetic and antioxidant characteristics.

應用

N-(tert-Butyl)hydroxylamine acetate has been used in a study to understand its effect on CD (cathepsin D) activity.
It may be used in the preparation of:

(Z)-α-5-bromo-N-tert-butyl-2-methoxyphenylnitrone
ONO-type pincer ligand
hydroxyphenyl nitrones

象形圖

GHS07

訊號詞

Warning

危險聲明

H315,H319,H335

防範說明

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves

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(Z)-α-5-Bromo-N-tert-butyl-2-methoxyphenylnitrone.

Guo H, et al.

Acta Crystallographica Section E, Structure Reports Online, 63(10), 3943-3943 (2007)

Microwave-assisted synthesis of hydroxyphenyl nitrones with protective action against oxidative stress.

Chavarria C, et al.

European Journal of Medicinal Chemistry, 58, 44-49 (2012)

Cln1 gene disruption in mice reveals a common pathogenic link between two of the most lethal childhood neurodegenerative lysosomal storage disorders.

Goutam Chandra et al.

Human molecular genetics, 24(19), 5416-5432 (2015-07-15)

Neurodegeneration is a devastating manifestation in the majority of >50 lysosomal storage disorders (LSDs). Neuronal ceroid lipofuscinoses (NCLs) are the most common childhood neurodegenerative LSDs. Mutations in 13 different genes (called CLNs) underlie various types of NCLs, of which the

Ruthenium ONO-Type Pincer Complex: Synthesis, Structural Characterization, and Catalysis.

Zhang Y, et al.

Advanced Synthesis & Catalysis, 352(10), 1779-1783 (2010)

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