20023

O-叔丁基羟胺 盐酸盐

≥99.0% (AT)

• 别名: 2-Aminooxy-2-methylpropane hydrochloride, O-(1,1-Dimethylethyl)hydroxylamine hydrochloride, tert-Butoxyamine hydrochloride
• 线性分子式: (CH₃)₃CONH₂ · HCl
• CAS号: 39684-28-1
• 分子量: 125.60
• Beilstein: 3668106
• EC號碼: 254-590-1
• MDL號碼: MFCD00043272
• 分類程式碼代碼: 12352100
• PubChem物質ID: 57647770
• NACRES: NA.22

属性

• 品質等級: 200
• 化驗: ≥99.0% (AT)
• 形狀: solid
• mp: ~155 °C (dec.)
• 溶解度: H₂O: soluble 0.5 g/10 mL
• SMILES 字串: Cl.CC(C)(C)ON
• InChI: 1S/C4H11NO.ClH/c1-4(2,3)6-5;/h5H2,1-3H3;1H
• InChI 密鑰: ZBDXGNXNXXPKJI-UHFFFAOYSA-N

说明

應用

O-tert-Butylhydroxylamine hydrochloride was used in the synthesis of N-methyl-O-tert-butylhydroxylamine hydrochloride. It was also used in the preparation of N-tert-butoxyamino acids as substrates for the unambiguous synthesis of N-hydroxy peptides.

Reactant involved in synthesis of biologically active molecules including:

• CGS 25966 derivatives for use as MMP inhibitors
• Imidazolidinedione derivatives for use as antimalarial treatments
• Pyrimidine ribonucleotide analogs as P2Y6 receptor agonists
• Rab proteins for isoprenylation and geranylgeranylation inhibition

Reactant involved in:

• Synthesis of N-(arylethyl)-O-tert-butylhydroxamates for use as Weinreb amide equivalents
• Double allylic alkylation of indole-2-hydroxamates
• SN2 substitution reactions at amide nitrogens
• Photocycloaddition to C=N bonds for synthesis of 1,3-diazepines

安全信息

• 象形圖: GHS02
• 訊號詞: Warning
• 危險聲明: H228
• 防範說明: P210
• 危險分類: Flam. Sol. 2
• 儲存類別代碼: 4.1B - Flammable solid hazardous materials
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges