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Merck

438227

Sigma-Aldrich

羟胺 溶液

50 wt. % in H2O

别名:

HDA

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About This Item

线性分子式:
NH2OH
CAS号:
分子量:
33.03
EC號碼:
MDL號碼:
分類程式碼代碼:
12352116
PubChem物質ID:
NACRES:
NA.22

蒸汽壓力

9 mmHg ( 40 °C)

品質等級

形狀

liquid

濃度

50 wt. % in H2O

bp

>100 °C

密度

1.078 g/mL at 25 °C

SMILES 字串

NO

InChI

1S/H3NO/c1-2/h2H,1H2

InChI 密鑰

AVXURJPOCDRRFD-UHFFFAOYSA-N

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一般說明

羟胺是一种弱碱,主要用作有机反应中的还原剂。

應用

作为制备下列化合物的反应物:
  • 心血管药物 Nω-羟基-L-精氨酸(NOHA,一氧化氮前体)的前药
  • 羟基氨基胍,作为抗癌药
  • 非甾体2,3-二氢喹啉糖皮质激素受体激动剂,具有降低的磷酸烯醇丙酮酸羧基激酶(PEPCK)转录激活活性
  • 氧氟沙星的羧酰胺衍生物,具有改善的抗菌特性
  • 基于香豆素类似物的TNF-α转化酶(TACE)抑制剂
  • HIV整合酶抑制剂

訊號詞

Danger

危險分類

Acute Tox. 4 Oral - Aquatic Acute 1 - Carc. 2 - Desen. Expl. 4 - Eye Dam. 1 - Met. Corr. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 - STOT SE 3

標靶器官

Blood, Respiratory system

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 3

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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