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Merck

108448

Sigma-Aldrich

氰基乙酰胺

99%

别名:

2-Cyanoacetamide

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About This Item

线性分子式:
NCCH2CONH2
CAS号:
分子量:
84.08
Beilstein:
878221
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

99%

mp

119-121 °C (lit.)

溶解度

cold water: soluble 1gm in 6.5ml

官能基

amide
nitrile

SMILES 字串

NC(=O)CC#N

InChI

1S/C3H4N2O/c4-2-1-3(5)6/h1H2,(H2,5,6)

InChI 密鑰

DGJMPUGMZIKDRO-UHFFFAOYSA-N

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一般說明

氰乙酰胺是合成维生素B6的起始试剂。它与硼酸缓冲液中的还原性碳水化合物反应,产生强烈的荧光,可用于碳水化合物作为硼酸盐络合物的自动分析

氰乙酰胺是一种高度反应性化合物,常用作缩合和取代反应中的反应中间体。

應用

氰基乙酰胺可用于荧光分光光度法对一些抗组胺H1受体拮抗剂药物进行测定,例如依巴斯汀、二盐酸西替利嗪、以及盐酸非索非那定。它可用于3,4-二羟基苯丙氨酸的荧光测定。它可用作兔血清中壳聚糖酯的生物分析和药代动力学的柱后荧光衍生剂。

象形圖

Exclamation mark

訊號詞

Warning

危險分類

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

419.0 °F - closed cup

閃點(°C)

215 °C - closed cup

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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Hao Chen et al.
Scientific reports, 8(1), 13433-13433 (2018-09-09)
Early damage to transplanted organs initiates excess inflammation that can cause ongoing injury, a leading cause for late graft loss. The endothelial glycocalyx modulates immune reactions and chemokine-mediated haptotaxis, potentially driving graft loss. In prior work, conditional deficiency of the
Fluorimetric determination of reducing carbohydrates with 2-cyanoacetamide and application to automated analysis of carbohydrates as borate complexes.
Honda S, et al.
Analytical Chemistry, 52(7), 1079-1082 (1980)
Fluorometric determination of 3, 4-dihydroxyphenylalanine with 2-cyanoacetamide.
Liu Y, et al.
Journal of Fluorescence, 13(2), 123-128 (2003)
Spectrofluorimetric Determination Of Some H1 Receptor Antagonist Drugs In Pharmaceutical Formulations And Biological Fluids.
Ibrahim F, et al.
International Journal of Pharmaceutical Sciences and Research, 2(8), 2056-2072 (2011)
Gregg A Duncan et al.
Molecular therapy. Methods & clinical development, 9, 296-304 (2018-07-25)
Diffusion of the viral vectors evaluated in inhaled gene therapy clinical trials to date are largely hindered within airway mucus, which limits their access to, and transduction of, the underlying airway epithelium prior to clearance from the lung. Here, we

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Knoevenagel Condensation is an organic reaction named after Emil Knoevenagel. It is a classic C-C bond formation reaction and a modification of the Aldol Condensation.

Knoevenagel Condensation is an organic reaction named after Emil Knoevenagel. It is a classic C-C bond formation reaction and a modification of the Aldol Condensation.

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