X7375

Xanthine

≥99%

• Sinónimos: 2,6-Dihydroxypurine
• Fórmula empírica (notación de Hill): C₅H₄N₄O₂
• Número de CAS: 69-89-6
• Peso molecular: 152.11
• Beilstein: 8733
• Número CE: 200-718-6
• Número MDL: MFCD00078453
• Código UNSPSC: 41106305
• ID de la sustancia en PubChem: 24902156
• NACRES: NA.51

Propiedades

• origen biológico: synthetic (organic)
• Nivel de calidad: 300
• Análisis: ≥99%
• formulario: powder
• solubilidad: 1 M NaOH: soluble 50 mg/mL, clear to slightly hazy; NH₄OH: freely soluble; NaOH: freely soluble
• cadena SMILES: O=C1NC(=O)c2nc[nH]c2N1
• InChI: 1S/C5H4N4O2/c10-4-2-3(7-1-6-2)8-5(11)9-4/h1H,(H3,6,7,8,9,10,11)
• Clave InChI: LRFVTYWOQMYALW-UHFFFAOYSA-N

Descripción

Descripción general

Xanthine is synthesized from guanine in the presence of guanine deaminase. Xanthine oxidase catalyzes the production of xanthine from hypoxanthine and its subsequent breakdown to uric acid. Xanthine derivatives are present in coffee, tea and cocoa seeds. Xanthine has been proposed as a lead for the generation of pharmacologically active compounds.

Aplicación

Xanthine has been used in a nonradiolabled substrate mix in an Aspergillus nidulans transport assay. It has also been used as a substrate for xanthine oxidase for superoxide anion generation in gill cells and algal cells.

Acciones bioquímicas o fisiológicas

A high level of xanthine is implicated in metabolic disorders like Lesch-Nyhan syndrome. A xanthine-based biosensor may be useful for detecting xanthine in food and clinical samples. Blood and urine samples of patients with renal failure, gout and xanthinuria show high levels of xanthine.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Equipo de protección personal: dust mask type N95 (US), Eyeshields, Faceshields, Gloves