X2502

Xanthine sodium salt

≥99%

• Sinónimos: 2,6-Dihydroxypurine
• Fórmula empírica (notación de Hill): C₅H₃N₄NaO₂
• Número de CAS: 1196-43-6
• Peso molecular: 174.09
• Número MDL: MFCD00069699
• Código UNSPSC: 41106305
• ID de la sustancia en PubChem: 24902137
• NACRES: NA.51

Propiedades

• origen biológico: synthetic (organic)
• Nivel de calidad: 200
• Ensayo: ≥99%
• Formulario: powder
• impurezas: ≤4% total solvent
• solubilidad: dilute NaOH: soluble, clear to slightly hazy
• cadena SMILES: [Na].O=C1NC(=O)c2[nH]cnc2N1
• InChI: 1S/C5H4N4O2.Na.H/c10-4-2-3(7-1-6-2)8-5(11)9-4;;/h1H,(H3,6,7,8,9,10,11);;
• Clave InChI: JAZQMXVZANZJSO-UHFFFAOYSA-N

Descripción

Descripción general

Xanthine is an intermediate of purine nucleotide metabolism. It is found in most body tissues and fluids. Xanthine derivatives are present in coffee, tea, and chocolate.

Aplicación

Xanthine sodium salt has been used as a component of substrate solution for xanthine oxidase during superoxide dismutase (SOD) assay. It has also been used as a supplement in a special-conditioned medium to culture Swiss 3T3 fibroblasts stably transfected with tetracycline (tet)-controlled transactivator and transactivator-controlled tissue transglutaminase cDNA [39] constructs (clone TG3).

Acciones bioquímicas o fisiológicas

Xanthine acts as a substrate for xanthine oxidase. It elevates cellular cyclic AMP levels by preventing its breakdown and metabolism by inhibition of tissue phosphodiesterases. Xanthine also exhibits anti-inflammatory properties either by the release of anti-inflammatory cytokines or gene transcription regulation or histone deacetylase activation. All these properties of xanthine aid in the relaxation of smooth muscles of the bronchial tree.

Información de seguridad

• Pictogramas: GHS08
• Palabra de señalización: Warning
• Frases de peligro: H371
• Consejos de prudencia: P260 - P264 - P270 - P308 + P311 - P405 - P501
• Clasificaciones de peligro: STOT SE 2
• Órganos de actuación: Eyes,Central nervous system
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: dust mask type N95 (US), Eyeshields, Faceshields, Gloves