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Merck

HRH1

histamine receptor H1

Sinónimos:
H1-R, hisH1
Especie:
ID UniProtKB:
ID del gen:
  • Human(3269) Summary: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene was thought to be intronless until recently. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(15465) histamine receptor H1
  • Rat(24448) histamine receptor H 1
  • Zebrafish(735302) histamine receptor H1
  • dog(403813) histamine receptor H1
  • domestic cat(101088314) histamine receptor H1
  • cow(281231) histamine receptor H1
  • Horse(100034110) histamine receptor H1
  • chicken(100858928) histamine receptor H1
  • domestic guinea pig(100135539) histamine receptor H1
  • domestic guinea pig(100730517) histamine receptor H1
  • naked mole-rat(101715481) histamine receptor H1
  • sheep(101121717) histamine receptor H1

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Small Molecule - Agonist

Referencia del producto
Descripción
Especie
Histamine dihydrochloride, ≥99.0% (AT),
Especie
human
Histamine, analytical standard,
Especie
human
Histamine dihydrochloride, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Histamine, European Pharmacopoeia (EP) Reference Standard,
Especie
human
Histamine dihydrochloride, European Pharmacopoeia (EP) Reference Standard,
Especie
human

Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
Pheniramine maleate, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Diphenhydramine hydrochloride, ≥98% (HPLC),
Especie
human
Cetirizine dihydrochloride, ≥98% (HPLC),
Especie
human
Promethazine hydrochloride, ,
Especie
human
Chlorpheniramine maleate, United States Pharmacopeia (USP) Reference Standard,
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Monoclonal Anti-HRH1 antibody produced in mouse, clone 3D1, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
proximity ligation assay
Anti-Histamine Receptor 1 Antibody, CT, Chemicon®, from rabbit,
Reactividad de especies
bovine, mouse, rat
Aplicación
ELISA
western blot

Small Molecule - Blocker

Referencia del producto
Descripción
Especie
Cinnarizine, European Pharmacopoeia (EP) Reference Standard,
Especie
human
Mianserin hydrochloride, ,
Especie
human
Cinnarizine, powder,
Especie
human
Orphenadrine hydrochloride, ≥98.0% (AT),
Especie
human
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Especie
human

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Ketotifen fumarate salt, ,
Especie
human
L-Histidinol dihydrochloride, ≥98 (TLC),
Especie
mouse, rat, human
D-Histidine monohydrochloride monohydrate, ≥98% (TLC),
Especie
mouse, rat, human
Loratadine, ≥98% (HPLC), powder,
Especie
rat, human
Histamine, ≥97.0%,
Especie
human, rat

Small Molecule - Ligand

Referencia del producto
Descripción
Especie
Loratadine, ≥98% (HPLC), powder,
Especie
rat, human
Cinnarizine, powder,
Especie
human

Small Molecule - Metabolite

Referencia del producto
Descripción
Especie
1-Methylhistamine dihydrochloride, ≥98% (TLC), powder,
Especie
human

Small Molecule - Mixed Agonist/Antagonist

Referencia del producto
Descripción
Especie
2-(2-Pyridyl)ethylamine, 95%,
Especie
human
Haloperidol, powder,
Especie
human, rat
Clozapine, ,
Especie
human, rat

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Hrh1,
Especie
mouse
MISSION® esiRNA, targeting human HRH1,
Especie
human