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AB5652P

Sigma-Aldrich

Anti-Histamine Receptor 1 Antibody, CT

Chemicon®, from rabbit

Sinónimos:

H1R

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

origen biológico

rabbit

Nivel de calidad

forma del anticuerpo

affinity purified immunoglobulin

tipo de anticuerpo

primary antibodies

clon

polyclonal

purificado por

affinity chromatography

reactividad de especies

bovine, mouse, rat

fabricante / nombre comercial

Chemicon®

técnicas

ELISA: suitable
western blot: suitable

Nº de acceso UniProt

Condiciones de envío

dry ice

modificación del objetivo postraduccional

unmodified

Información sobre el gen

mouse ... Hrh1(15465)
rat ... Hrh1(24448)

Especificidad

Recognizes rat Histamine Receptor 1 (HR1). The immunogen shows no significant sequence homology with other histamine receptors.

The immunogen peptide is 100% conserved in mouse and bovine, 94% in human, fish and monkey and 80% in guinea pig. Reactivity with other species has not been confirmed.

Inmunógeno

A 17 amino acid peptide sequence near the cytoplasmic, C-terminus of rat HR1 (Fujimoto et al. 1993; Inoue et al. 1996; DeBacker et al. 1993; Fukui et al. 1994; Moguilevsky et al. 1994).
Epitope: C-terminus

Aplicación

Research Category
Inflammation & Immunology
Research Sub Category
Inflammation & Autoimmune Mechanisms
This Anti-Histamine Receptor 1 Antibody, C-terminus is validated for use in ELISA, WB for the detection of Histamine Receptor 1.
Western blot: 1-10 μg/mL using ECL. Recognizes a 57kDa band representing the H1 receptor

ELISA: 1:10,000-1:100,000 using 50-100 ng control peptide per well.

Optimal working dilutions must be determined by the end user.

Forma física

Affinity purified immunoglobulin. Liquid in PBS containing 0.1% BSA.

Almacenamiento y estabilidad

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Información legal

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Histamine-induced ion secretion across rat distal colon: involvement of histamine H1 and H2 receptors.
Gerhard Schultheiss, Britta Hennig, Walter Schunack, Gundula Prinz, Martin Diener
European Journal of Pharmacology null
Extraction of membrane cholesterol disrupts caveolae and impairs serotonergic (5-HT2A) and histaminergic (H1) responses in bovine airway smooth muscle: role of Rho-kinase.
Bettina Sommer,Luis M Monta?o,Veronica Carbajal,Edgar Flores-Soto,Alicia Ortega et al.
Canadian Journal of Physiology and Pharmacology null
Matthew J Gastinger et al.
The Journal of comparative neurology, 495(6), 658-667 (2006-03-01)
Mammalian retinas are innervated by histaminergic axons that originate from perikarya in the posterior hypothalamus. To identify the targets of these retinopetal axons, we localized histamine receptors (HR) in monkey and rat retinas by light and electron microscopy. In monkeys
Kathryn M Lenz et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 38(37), 8044-8059 (2018-08-11)
Many sex differences in brain and behavior are programmed during development by gonadal hormones, but the cellular mechanisms are incompletely understood. We found that immune-system-derived mast cells are a primary target for the masculinizing hormone estradiol and that mast cells

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