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59964

Supelco

Histamine

analytical standard

Sinónimos:

2-(4-Imidazolyl)ethylamine

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About This Item

Fórmula empírica (notación de Hill):
C5H9N3
Número de CAS:
51-45-6
Peso molecular:
111.15
Beilstein:
2012
Número CE:
200-100-6
Número MDL:
MFCD00005210
Código UNSPSC:
85151701
ID de la sustancia en PubChem:
329758639
NACRES:
NA.24

grado

analytical standard

Nivel de calidad

100

Análisis

≥97.0% (TLC)
≥97.0% (anhydrous basis, NT)

caducidad

limited shelf life, expiry date on the label

técnicas

HPLC: suitable
gas chromatography (GC): suitable

impurezas

≤4.0% water

color

white to light yellow

bp

167 °C/0.8 mmHg (lit.)

mp

83-84 °C (lit.)

formato

neat

temp. de almacenamiento

−20°C

cadena SMILES

NCCc1c[nH]cn1

InChI

1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)

Clave InChI

NTYJJOPFIAHURM-UHFFFAOYSA-N

Información sobre el gen

human ... HRH1(3269)

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Aplicación

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Acciones bioquímicas o fisiológicas

Endogenous H1 and H2 histamine receptor agonist; H1 activation mobilizes Ca2+; H2 activation stimulates adenylate cyclase activity in neurons; activates nitric oxide synthetase; potent vasodilator.

Pictogramas

Skull and crossbonesHealth hazard
GHS06,GHS08

Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 3 Oral - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Órganos de actuación

Respiratory system

Código de clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Choose from one of the most recent versions:

Certificados de análisis (COA)

Lot/Batch Number
BCCD9621
BCCC7505
BCCB6982
BCBV8838
BCBW3895

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If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

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Histamine bisphosphate monohydrate ≥99.0% (NT)

Sigma-Aldrich

53310

Histamine bisphosphate monohydrate

Ye Zhang et al.
Investigative ophthalmology & visual science, 56(1), 563-570 (2015-01-13)
We estimate and compare change in iris cross-sectional area (IA) after physiologic and pharmacologic mydriasis in subjects with different dominant mechanisms for primary angle closure. Anterior segment optical coherence tomography (AS-OCT) measurements in light, dark, and following pharmacologic dilation were
Mohamed H Shamji et al.
The Journal of allergy and clinical immunology, 135(4), 913-921 (2014-12-03)
Immunotherapy inhibits basophil histamine release, but the assay is cumbersome, and no one has studied the effects of immunotherapy withdrawal. Intracellular fluorochrome-labeled diamine oxidase (DAO) was used as a novel functional readout of basophil histamine release after immunotherapy. Results were
P J Turner et al.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 25(7), 657-661 (2014-10-10)
Most children with egg allergy tolerate egg in baked foods, such as cake, but tolerance cannot be predicted with conventional allergy testing. We hypothesized that the skin prick test (SPT) wheal to unprocessed raw egg might predict tolerance of baked
Andrea Strasser et al.
Trends in pharmacological sciences, 34(1), 13-32 (2012-12-12)
Histamine is a biogenic amine that exerts its biological effects as a neurotransmitter and local mediator via four histamine receptor (HR) subtypes (H(x)Rs) - H(1)R, H(2)R, H(3)R, and H(4)R - belonging to the superfamily of G-protein-coupled receptors (GPCRs). All four
Ruth Ferstl et al.
Frontiers in bioscience (Landmark edition), 17, 40-53 (2011-12-29)
Histamine influences many cell types involved in the regulation of innate and adaptive immune responses including antigen-presenting cells (APCs), Natural Killer (NK) cells, epithelial cells, T lymphocytes and B lymphocytes. These cells express histamine receptors (HRs) and also secrete histamine
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