Passa al contenuto
Merck
Tutte le immagini(1)

Documenti fondamentali

Visualizza tutta la documentazione

1535008

USP

Phenytoin

United States Pharmacopeia (USP) Reference Standard

Sinonimo/i:

5,5-Diphenylhydantoin, 5,5-Diphenyl-2,4-imidazolidinedione, Phenytoin

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
Tutte le immagini(1)

About This Item

Formula empirica (notazione di Hill):
C15H12N2O2
Numero CAS:
57-41-0
Peso molecolare:
252.27
Beilstein:
384532
Numero MDL:
MFCD00005264
Codice UNSPSC:
41116107
ID PubChem:
329750826
NACRES:
NA.24

Grado

pharmaceutical primary standard

Famiglia di API

phenytoin

Produttore/marchio commerciale

USP

Punto di fusione

293-295 °C (lit.)

applicazioni

pharmaceutical (small molecule)

Formato

neat

Stringa SMILE

O=C1NC(=O)C(N1)(c2ccccc2)c3ccccc3

InChI

1S/C15H12N2O2/c18-13-15(17-14(19)16-13,11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H,(H2,16,17,18,19)
CXOFVDLJLONNDW-UHFFFAOYSA-N

Informazioni sul gene

human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

Cerchi prodotti simili? Visita Guida al confronto tra prodotti

Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Phenytoin USP Reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Phenytoin Sodium
  • Phenytoin Chewable Tablets
  • Phenytoin Oral Suspension
  • Phenytoin Sodium Injection
  • Extended Phenytoin Sodium Capsules
  • Phenytoin Compounded Topical Gel
  • Fosphenytoin Sodium Injection

Azioni biochim/fisiol

Anticonvulsant.
Reduces incidence of grand mal seizures; appears to stabilize excitable membranes perhaps through effects on Na+, K+, and Ca2+ channels.

Risultati analitici

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Esclusione di responsabilità

Sales restrictions may apply.

Prodotti correlati

N° Catalogo
Descrizione
Determinazione del prezzo

1535019

Phenytoin Related Compound A, United States Pharmacopeia (USP) Reference Standard

1535507

Phenytoin sodium, United States Pharmacopeia (USP) Reference Standard

1535020

Phenytoin Related Compound B, United States Pharmacopeia (USP) Reference Standard

P1290000

Phenytoin, European Pharmacopoeia (EP) Reference Standard

P1300000

Phenytoin sodium, European Pharmacopoeia (EP) Reference Standard

Y0001167

Phenytoin for system suitability, European Pharmacopoeia (EP) Reference Standard

PHR1492

Phenytoin sodium, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1574

Phenytoin Related Compound A, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1692

Phenytoin Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material

BP1238

Phenytoin sodium, British Pharmacopoeia (BP) Reference Standard

PHR2246

1-Methyl-5,5-diphenylimidazolidine-2,4-dione, Pharmaceutical Secondary Standard; Certified Reference Material

PHR9055

Benzil, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

PHR2247

5-(4-Methylphenyl)hydantoin

PHR2553

Phenytoin Impurity F, Pharmaceutical Secondary Standard; Certified Reference Material

Pittogrammi

Health hazardExclamation mark
GHS08,GHS07

Avvertenze

Danger

Indicazioni di pericolo

H302,H351,H360FD

Classi di pericolo

Acute Tox. 4 Oral - Carc. 2 - Repr. 1B

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documenti section.

Se ti serve aiuto, non esitare a contattarci Servizio Clienti

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

I clienti hanno visto anche

Slide 1 of 7

1 of 7

5,5-Diphenylhydantoin sodium salt ≥99%

Sigma-Aldrich

D4505

5,5-Diphenylhydantoin sodium salt

Disopyramide European Pharmacopoeia (EP) Reference Standard

D2920000

Disopyramide

Carbamazepine powder

Sigma-Aldrich

C4024

Carbamazepine

Topiramate ≥98% (HPLC), solid

Sigma-Aldrich

T0575

Topiramate

Pentylenetetrazole

Sigma-Aldrich

P6500

Pentylenetetrazole

Valproic acid United States Pharmacopeia (USP) Reference Standard

USP

1708707

Valproic acid

Lidocaine powder

Sigma-Aldrich

L7757

Lidocaine

Deborah Pugin et al.
Critical care (London, England), 18(3), R103-R103 (2014-06-03)
Seizures refractory to third-line therapy are also labeled super-refractory status epilepticus (SRSE). These seizures are extremely difficult to control and associated with poor outcome. We aimed to characterize efficacy and side-effects of continuous infusions of pentobarbital (cIV-PTB) treating SRSE. We
Chunhong Shen et al.
Bone, 64, 246-253 (2014-05-02)
It has been shown that antiepileptic drugs (AEDs) may have a detrimental effect on bone health and translate into an increased risk of bone fracture. We aimed to comprehensively evaluate the association between use of AEDs and fracture risk. We
Syed Nabeel Zafar et al.
BMC neurology, 12, 30-30 (2012-05-31)
Current standard therapy for seizure prophylaxis in Neuro-surgical patients involves the use of Phenytoin (PHY). However, a new drug Levetiracetam (LEV) is emerging as an alternate treatment choice. We aimed to conduct a meta-analysis to compare these two drugs in
Lelia Duley et al.
The Cochrane database of systematic reviews, (10)(10), CD000128-CD000128 (2010-10-12)
Eclampsia, the occurrence of a seizure in association with pre-eclampsia, remains a rare but serious complication of pregnancy. A number of different anticonvulsants have been used to control eclamptic fits and to prevent further seizures. The objective of this review
P J Smith et al.
Endocrine reviews, 5(4), 514-524 (1984-01-01)
The studies described above indicate the likelihood of a significant effect of DPH on cellular functions that are regulated by T3 at concentrations of DPH that occur during treatment of patients with Dilantin. Thus, it is possible that sensitive measures
Visualizza tutti i documenti correlati

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.