1338313

Imiquimod

United States Pharmacopeia (USP) Reference Standard

• Sinonimo/i: 1-(2-Methylpropyl)-1H-imidazole[4,5-c]quinoline-4-amine
• Formula empirica (notazione di Hill): C₁₄H₁₆N₄
• Numero CAS: 99011-02-6
• Peso molecolare: 240.30
• Numero MDL: MFCD00866946
• Codice UNSPSC: 41116107
• ID PubChem: 329750158
• NACRES: NA.24

Proprietà

• Grado: pharmaceutical primary standard
• Famiglia di API: imiquimod
• Produttore/marchio commerciale: USP
• applicazioni: pharmaceutical (small molecule)
• Formato: neat
• Stringa SMILE: CC(C)Cn1cnc2c(N)nc3ccccc3c12
• InChI: 1S/C14H16N4/c1-9(2)7-18-8-16-12-13(18)10-5-3-4-6-11(10)17-14(12)15/h3-6,8-9H,7H2,1-2H3,(H2,15,17); DOUYETYNHWVLEO-UHFFFAOYSA-N
• Informazioni sul gene: human ... TLR7(51284)

Descrizione

Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Imiquimod USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Imiquimod Cream

Azioni biochim/fisiol

Imiquimod is a caspase 3 activator, which directly induces procaspase 3 cleavage to active caspase 3. Imiquimod induces apoptosis in vivo in basal cell carcinoma. Its anti-tumor activity is related to the induction of apoptosis. Imiquimod has anti-angiogenic, anti-inflammatory, anti-viral activities. Imiquimod also acts as an immune response modulator inducing the secretion of various cytokines and chemokines.

Imiquimod is a caspase 3 activator, which directly induces procaspase 3 cleavage to active caspase 3. Imiquimod induces apoptosis in vivo and acts as an immunomodulator with anti-viral and anti-inflammatory perties.

Risultati analitici

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Altre note

Sales restrictions may apply.

Informazioni sulla sicurezza

• Pittogrammi: GHS06
• Avvertenze: Danger
• Indicazioni di pericolo: H301,H315,H319
• Consigli di prudenza: P264 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338 - P332 + P313
• Classi di pericolo: Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2
• Codice della classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable